Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.45 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 5/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 5/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 5/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14368066 | 0.84 | ADRA1D (0.56) | TRIM24ALOX15ALOX12ADRA1DADRA1A | |
| SCHEMBL23823918 | 0.84 | TRIM24 (0.50) | TRIM24ALOX15ALOX12LDHAADRA1D | |
| SCHEMBL13623710 | 0.84 | TRPV4 (0.40) | TRPV4TRIM24ALOX15ALOX12LDHA | |
| SCHEMBL741235 | 0.82 | ALPL (0.51) | TRPV4SMN1; SMN2 | |
| SCHEMBL8180786 | 0.79 | TRPV4 (0.46) | TRPV4ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL5903990 | 0.79 | ACACB (0.45) | TRIM24LDHAADRA1DADRA1AADRA1B | |
| SCHEMBL5807725 | 0.79 | ACACB (0.45) | TRIM24LDHAADRA1DADRA1AADRA1B | |
| SCHEMBL9724436 | 0.77 | CA5A (0.61) | TRPV4ALDH1A1GAA | |
| SCHEMBL30997420 | 0.77 | CA5A (0.47) | TRPV4ALDH1A1SMN1; SMN2GAA | |
| SCHEMBL4660848 | 0.77 | CA5A (0.47) | TRPV4ALDH1A1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11357873-B2 | Chiral cyclen compounds and their uses | THE HONG KONG POLYTECHNIC UNIVERSITY (CN) | 2022-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11357873-B2 | Chiral cyclen compounds and their uses | DCTN3, DCTN1, CDK3 | TRPV4 3080/4885TRIM24 4769/4885ALOX15 4628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.