Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.60 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | CA9 | Q16790 | 1/20 | 0.55 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.48 |
| ▸ | RBP4 | P02753 | 1/20 | 0.46 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.46 |
| ▸ | OGA | O60502 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP1 | P63208 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5232026 | 0.84 | SLC6A7 (0.68) | PKMSLC6A7ADRB1CA12CA1 | |
| SCHEMBL8354208 | 0.82 | ADRB1 (0.78) | PKMSLC6A7ADRB1CA12CA1 | |
| SCHEMBL3069202 | 0.80 | PKM (0.77) | PKMSLC6A7ADRB1CA12CA1 | |
| SCHEMBL8356355 | 0.79 | PKM (0.91) | PKMSLC6A7ADRB1CA12CA1 | |
| SCHEMBL18499227 | 0.78 | PKM (0.60) | PKMSLC6A7ADRB1CA12CA1 | |
| SCHEMBL15503742 | 0.78 | PKM (0.63) | PKMSLC6A7ADRB1CA12CA1 | |
| SCHEMBL24963646 | 0.78 | ACHE (0.59) | PKMSLC6A7ADRB1CA12CA1 | |
| SCHEMBL5887976 | 0.77 | KDM4E (0.60) | SLC6A7KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL9108819 | 0.77 | PARP1 (0.56) | PKMSLC6A7ADRB1CA12CA1 | |
| SCHEMBL27077801 | 0.76 | TIPARP (0.53) | ALDH1A1KMT2ACHRM2MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060122234-A1 | Substituted thienyl-hydroxamic acids as histone deacetylase inhibitors | ARGENTA DISCOVERY LIMITED | 2006-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060122234-A1 | Substituted thienyl-hydroxamic acids as histone deacetylase inhibitors | HDAC1, HDAC11, HDAC2 | PKM 1380/4885SLC6A7 1383/4885ADRB1 4320/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.