Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BHMT | Q93088 | 11/20 | 0.57 |
| ▸ | BHMT2 | Q9H2M3 | 1/20 | 0.57 |
| ▸ | NOS2 | P35228 | 2/20 | 0.53 |
| ▸ | NOS3 | P29474 | 1/20 | 0.53 |
| ▸ | NOS1 | P29475 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119412 | 0.91 | BHMT (0.67) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL474911 | 0.91 | BHMT (0.67) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL474910 | 0.91 | BHMT (0.67) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL4460278 | 0.90 | BHMT (0.57) | BHMTBHMT2NOS2NOS3NOS1 | |
| Hydrochloric Acid SCHEMBL28941785 | 0.89 | BHMT (0.65) | BHMTBHMT2NOS2NOS3NOS1 | |
| Ethionine SCHEMBL840667 | 0.88 | BHMT (0.54) | BHMTBHMT2NOS2NOS3NOS1 | |
| Ethionine SCHEMBL840665 | 0.88 | BHMT (0.54) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL1031686 | 0.81 | BHMT (0.76) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL21851894 | 0.81 | BHMT (0.76) | BHMTBHMT2NOS2NOS3NOS1 | |
| SCHEMBL1031684 | 0.81 | BHMT (0.76) | BHMTBHMT2NOS2NOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060142251-A1 | Anti-microbial agents derived from methionine sulfoximine analogues | MEDICAL COLLEGE OF WISCONSIN | 2006-06-29 | — | — | US | disclosed |
| US-20040157802-A1 | Anti-microbial agents derived from methionine sulfoximine analogues | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2004-08-12 | — | — | US | disclosed |
| WO-2004045539-A9 | ANTI-MICROBIAL AGENTS DERIVED FROM METHIONINE SULFOXIMINE ANALOGUES | UNIV CALIFORNIA (US) | 2004-08-05 | — | — | WO | disclosed |
| WO-2004045539-A2 | ANTI-MICROBIAL AGENTS DERIVED FROM METHIONINE SULFOXIMINE ANALOGUES | REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2004-06-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157802-A1 | Anti-microbial agents derived from methionine sulfoximine analogues | MTR, MSRB3, LPO | BHMT 59/4885BHMT2 38/4885NOS2 301/4885 |
| US-20060142251-A1 | Anti-microbial agents derived from methionine sulfoximine analogues | MTR, MSRB3, LPO | BHMT 59/4885BHMT2 36/4885NOS2 345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.