Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SETD7 | Q8WTS6 | 2/20 | 0.60 |
| ▸ | SIGMAR1 | Q99720 | 10/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035852 | 0.80 | SETD7 (0.68) | SETD7SIGMAR1HRH1MC4RHTR1A | |
| Hydrochloric Acid SCHEMBL7213868 | 0.79 | SETD7 (0.66) | SETD7SIGMAR1HRH1MC4RHTR1A | |
| SCHEMBL11092367 | 0.78 | SIGMAR1 (0.61) | SIGMAR1MC4RHTR1AADRA2AADRA2B | |
| SCHEMBL5905710 | 0.76 | SETD7 (1.00) | SETD7HRH1HTR1AADRA2AADRA2B | |
| SCHEMBL12785914 | 0.75 | LMNA (0.49) | SIGMAR1 | |
| SCHEMBL11576057 | 0.74 | SETD7 (0.55) | SETD7HRH1HTR1AADRA2AADRA2B | |
| SCHEMBL11600100 | 0.73 | SETD7 (0.61) | SETD7HRH1HTR1AADRA2AADRA2B | |
| SCHEMBL8892053 | 0.72 | SIGMAR1 (0.50) | SIGMAR1ABCB1MC4RDRD4 | |
| SCHEMBL11576476 | 0.72 | SETD7 (0.56) | SETD7SIGMAR1HRH1HTR1AADRA2A | |
| SCHEMBL15920200 | 0.72 | SIGMAR1 (0.47) | SIGMAR1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060111342-A1 | Insecticidal tricyclic derivatives | BAYER CROPSCIENCE AG (DE) | 2006-05-25 | — | — | US | disclosed |
| EP-1538906-A2 | INSECTICIDAL TRICYCLIC DERIVATIVES | FMC CORPORATION (US) | 2005-06-15 | — | — | EP | disclosed |
| WO-2004026030-A2 | INSECTICIDAL TRICYCLIC DERIVATIVES | FMC CORPORATION (US) | 2004-04-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111342-A1 | Insecticidal tricyclic derivatives | DDT, ACHE, ODC1 | SETD7 1641/4885SIGMAR1 192/4885ABCB1 775/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.