Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 7/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906074 | 0.90 | ROCK2 (0.41) | ROCK2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5906254 | 0.89 | MAPT (0.43) | ROCK2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5906339 | 0.89 | ROCK2 (0.40) | ROCK2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5906022 | 0.88 | ADORA3 (0.39) | ROCK2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5906041 | 0.88 | POLB (0.43) | ROCK2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5906188 | 0.88 | ROCK2 (0.48) | ROCK2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5906249 | 0.87 | ROCK2 (0.49) | ROCK2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5906235 | 0.87 | TSHR (0.50) | ADORA3ADORA2AADORA2BADORA1MEN1 | |
| SCHEMBL5906139 | 0.86 | ADORA3 (0.39) | ROCK2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5906320 | 0.86 | ADORA3 (0.39) | ROCK2ADORA3ADORA2AADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060223872-A1 | Insecticidal phthalamide derivatives | BAYER CROPSCIENCE AG (DE) | 2006-10-05 | — | — | US | disclosed |
| EP-1606271-A1 | INSECTICIDAL PHTHALAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2005-12-21 | — | — | EP | disclosed |
| WO-2004080984-A1 | INSECTICIDAL PHTHALAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2004-09-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223872-A1 | Insecticidal phthalamide derivatives | CRYAA, PRXL2A, H1-2 | ROCK2 1976/4885ADORA3 2149/4885ADORA2A 2889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.