SCHEMBL5906038

SCHEMBL5906038

Cc1cc(Cn2nnn(Cc3ccccc3)c2=O)ccc1[N+](=O)[O-]

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.48
BLM P54132 1/20 0.48
MEN1 O00255 5/20 0.46
KMT2A Q03164 5/20 0.46
HSD17B10 Q99714 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 1/20 0.43
MAPK1 P28482 1/20 0.43
NPBWR1 P48145 1/20 0.42
MCHR1 Q99705 1/20 0.42
LMNA P02545 1/20 0.41
TSHR P16473 2/20 0.40
CYP1A2 P05177 2/20 0.40
CYP2C19 P33261 2/20 0.40
POLB P06746 1/20 0.40
CYP2C9 P11712 1/20 0.40
HPGD P15428 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5906347 0.90 LMNA (0.48) L3MBTL1BLMMEN1KMT2ASMN1; SMN2
SCHEMBL5905866 0.89 KMT2A (0.49) L3MBTL1BLMMEN1KMT2ASMN1; SMN2
SCHEMBL5906039 0.88 MAPT (0.39) L3MBTL1BLMMEN1KMT2AHSD17B10
SCHEMBL5906411 0.88 MEN1 (0.46) L3MBTL1BLMMEN1KMT2AHSD17B10
SCHEMBL5906279 0.86 MAPT (0.38) L3MBTL1BLMMEN1KMT2AHSD17B10
SCHEMBL5906184 0.86 TSHR (0.41) L3MBTL1BLMMEN1KMT2AHSD17B10
SCHEMBL5906051 0.85 SMN1; SMN2 (0.41) SMN1; SMN2ALDH1A1KDM4ECYP1A2CYP2C19
SCHEMBL5906329 0.85 ALDH1A1 (0.39) L3MBTL1BLMMEN1KMT2AHSD17B10
SCHEMBL5906343 0.84 ALDH1A1 (0.42) L3MBTL1BLMMEN1KMT2AHSD17B10
SCHEMBL5906024 0.84 ALDH1A1 (0.50) L3MBTL1BLMMEN1KMT2AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060223872-A1 Insecticidal phthalamide derivatives BAYER CROPSCIENCE AG (DE) 2006-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060223872-A1 Insecticidal phthalamide derivatives CRYAA, PRXL2A, H1-2 L3MBTL1 485/4885BLM 1200/4885MEN1 477/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.