Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 6/20 | 0.45 |
| ▸ | PPARD | Q03181 | 10/20 | 0.43 |
| ▸ | PPARA | Q07869 | 10/20 | 0.43 |
| ▸ | PPARG | P37231 | 8/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.36 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | KDR | P35968 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1829217 | 0.97 | PPARD (0.45) | ROCK2PPARDPPARAPPARG | |
| SCHEMBL5906392 | 0.94 | ROCK2 (0.43) | ROCK2PPARDPPARAPPARG | |
| SCHEMBL1827020 | 0.88 | PPARG (0.39) | ROCK2PPARDPPARAPPARG | |
| SCHEMBL1829886 | 0.85 | PPARG (0.44) | PPARDPPARAPPARG | |
| SCHEMBL5906188 | 0.84 | ROCK2 (0.48) | ROCK2PPARDPPARAPPARG | |
| SCHEMBL5906424 | 0.84 | ROCK2 (0.38) | ROCK2PPARDPPARAPPARG | |
| SCHEMBL5906074 | 0.84 | ROCK2 (0.41) | ROCK2PPARDPPARAPPARG | |
| SCHEMBL5906232 | 0.84 | ROCK2 (0.38) | ROCK2PPARDPPARAPPARG | |
| SCHEMBL5905914 | 0.84 | ROCK2 (0.42) | ROCK2PPARDPPARAPPARGCYP2C9 | |
| SCHEMBL5906426 | 0.84 | PPARD (0.44) | ROCK2PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060223872-A1 | Insecticidal phthalamide derivatives | BAYER CROPSCIENCE AG (DE) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223872-A1 | Insecticidal phthalamide derivatives | CRYAA, PRXL2A, H1-2 | ROCK2 1976/4885PPARD 3684/4885PPARA 2780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.