Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 9/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 7/20 | 0.36 |
| ▸ | PPARD | Q03181 | 7/20 | 0.36 |
| ▸ | PPARA | Q07869 | 7/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906362 | 0.92 | AR (0.41) | ROCK2 | |
| SCHEMBL5906265 | 0.91 | NOTUM (0.48) | ROCK2NOTUM | |
| SCHEMBL1829217 | 0.87 | PPARD (0.45) | ROCK2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL1827020 | 0.84 | PPARG (0.39) | ROCK2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL1829886 | 0.84 | PPARG (0.44) | PPARGPPARDPPARAKDM4EMAPT | |
| SCHEMBL5906397 | 0.84 | ROCK2 (0.45) | ROCK2PPARGPPARDPPARA | |
| SCHEMBL5906177 | 0.83 | AR (0.41) | ROCK2PPARGPPARDPPARANOTUM | |
| SCHEMBL5906188 | 0.83 | ROCK2 (0.48) | ROCK2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5906074 | 0.83 | ROCK2 (0.41) | ROCK2ADORA3ADORA2AADORA2BADORA1 | |
| SCHEMBL5906250 | 0.83 | PPARG (0.43) | ADORA3ADORA2AADORA2BADORA1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060223872-A1 | Insecticidal phthalamide derivatives | BAYER CROPSCIENCE AG (DE) | 2006-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223872-A1 | Insecticidal phthalamide derivatives | CRYAA, PRXL2A, H1-2 | ROCK2 1976/4885ADORA3 2149/4885ADORA2A 2889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.