Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | IKBKB | O14920 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | NPR3 | P17342 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
| ▸ | TACR3 | P29371 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906821 | 1.00 | ALDH1A1 (0.47) | ALDH1A1KDM4ELMNAIKBKBKMT2A | |
| SCHEMBL5906911 | 0.91 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAIKBKBKMT2A | |
| SCHEMBL5906906 | 0.91 | ALDH1A1 (0.48) | ALDH1A1KDM4ELMNAIKBKBKMT2A | |
| SCHEMBL5906787 | 0.82 | CLK1 (0.47) | ALDH1A1KDM4EIKBKBKMT2AMEN1 | |
| SCHEMBL5906791 | 0.82 | CLK1 (0.47) | ALDH1A1KDM4EIKBKBKMT2AMEN1 | |
| SCHEMBL5906647 | 0.82 | DYRK1A (0.45) | HDAC1NPR3JAK2JAK3TACR3 | |
| SCHEMBL5906648 | 0.82 | DYRK1A (0.45) | HDAC1NPR3JAK2JAK3TACR3 | |
| SCHEMBL5906859 | 0.82 | NOS2 (0.47) | HDAC1JAK2JAK3TACR3 | |
| SCHEMBL5906845 | 0.81 | KMO (0.45) | ALDH1A1KDM4ELMNAKMT2AMAPT | |
| SCHEMBL5906849 | 0.81 | KMO (0.45) | ALDH1A1KDM4ELMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089371-A1 | Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist | BAYER HEALTHCARE AG (DE) | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089371-A1 | Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist | BPHL, HRH4, HRH2 | ALDH1A1 655/4885KDM4E 1339/4885LMNA 2179/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.