Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS2 | P35228 | 4/20 | 0.47 |
| ▸ | NOS3 | P29474 | 2/20 | 0.47 |
| ▸ | NOS1 | P29475 | 2/20 | 0.47 |
| ▸ | TACR3 | P29371 | 1/20 | 0.45 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 1/20 | 0.40 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5906791 | 0.87 | CLK1 (0.47) | TACR3GPR142MAPK8PIK3CGCAMKK2 | |
| SCHEMBL5906787 | 0.87 | CLK1 (0.47) | TACR3GPR142MAPK8PIK3CGCAMKK2 | |
| SCHEMBL5906648 | 0.84 | DYRK1A (0.45) | TACR3GPR142MAPK8PIK3CGCAMKK2 | |
| SCHEMBL5906647 | 0.84 | DYRK1A (0.45) | TACR3GPR142MAPK8PIK3CGCAMKK2 | |
| SCHEMBL5906821 | 0.82 | ALDH1A1 (0.47) | TACR3HDAC1JAK2JAK3 | |
| SCHEMBL5906823 | 0.82 | ALDH1A1 (0.47) | TACR3HDAC1JAK2JAK3 | |
| SCHEMBL5906846 | 0.81 | NPR3 (0.55) | TACR3GPR142HDAC1HDAC6JAK2 | |
| SCHEMBL5906718 | 0.80 | NOS2 (0.47) | NOS2NOS3NOS1TACR3HDAC1 | |
| SCHEMBL5906633 | 0.80 | NOS2 (0.47) | NOS2NOS3NOS1TACR3HDAC1 | |
| SCHEMBL5906632 | 0.80 | NOS2 (0.47) | NOS2NOS3NOS1TACR3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060089371-A1 | Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist | BAYER HEALTHCARE AG (DE) | 2006-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060089371-A1 | Phenyl or heteroaryl amino alkane derivatives as ip receptor antagonist | BPHL, HRH4, HRH2 | NOS2 2103/4885NOS3 2582/4885NOS1 3240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.