Butane

Butane

SCHEMBL5906885

CCCC.O=C(O)CCC(=O)OC(=O)CCC(=O)OC(=O)CCC(=O)O

nearest known ligand 0.62

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.62
FFAR3 O14843 2/20 0.52
HDAC3 O15379 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC2 Q92769 1/20 0.52
HDAC8 Q9BY41 1/20 0.52
EGLN1 Q9GZT9 2/20 0.50
KDM6B O15054 1/20 0.50
KDM5C P41229 1/20 0.50
PHF8 Q9UPP1 1/20 0.50
KDM2A Q9Y2K7 1/20 0.50
LMNA P02545 2/20 0.47
ALKBH5 Q6P6C2 1/20 0.47
SUCNR1 Q9BXA5 1/20 0.47
AKR1B1 P15121 1/20 0.46
GPR84 Q9NQS5 7/20 0.44
PPARG P37231 7/20 0.44
PPARD Q03181 7/20 0.44
PPARA Q07869 7/20 0.44
HDAC11 Q96DB2 5/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butane SCHEMBL11515950 0.95 ALDH1A1 (0.71) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL2100646 0.92 ALDH1A1 (0.75) ALDH1A1FFAR3HDAC3HDAC1HDAC2
Succinic Acid SCHEMBL28781419 0.92 ALDH1A1 (0.75) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL9980506 0.90 ALDH1A1 (0.55) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL288701 0.89 LMNA (0.60) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL1992862 0.89 LMNA (0.60) ALDH1A1FFAR3HDAC3HDAC1HDAC2
Butane SCHEMBL6656493 0.88 ALDH1A1 (0.48) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL15845145 0.86 AKR1B1 (0.62) ALDH1A1AKR1B1GPR84PPARGPPARD
SCHEMBL27705671 0.86 LMNA (0.56) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL27749051 0.86 LMNA (0.56) ALDH1A1FFAR3HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114956985-B Method for preparing 2, 5-dihydroxyterephthalic acid by oxygen oxidation 天津科技大学 2023-10-20 CN claimed
CN-109180922-B Low-temperature curing type polyester resin and preparation method and application thereof ANHUI HENG LONG NEW MATERIAL Co.,Ltd. (CN) 2021-06-22 CN claimed
CN-210340737-U Organic chemical pigment production preparation facilities 浙江永泉化学有限公司 2020-04-17 CN claimed
CN-115819202-B Method for synthesizing cyclohexanedione 邯郸市瑞田农药有限公司 2024-03-12 CN disclosed
CN-114956985-B Method for preparing 2, 5-dihydroxyterephthalic acid by oxygen oxidation 天津科技大学 2023-10-20 CN disclosed
CN-115819202-A Method for synthesizing cyclohexanedione 邯郸市瑞田农药有限公司 2023-03-21 CN disclosed
CN-114956985-A Method for preparing 2, 5-dihydroxy terephthalic acid by oxygen oxidation 天津科技大学 2022-08-30 CN disclosed
US-11244797-B2 Flying vehicle current interruption device NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2022-02-08 US disclosed
CN-109180922-B Low-temperature curing type polyester resin and preparation method and application thereof ANHUI HENG LONG NEW MATERIAL Co.,Ltd. (CN) 2021-06-22 CN disclosed
CN-109180922-B Low-temperature curing type polyester resin and preparation method and application thereof ANHUI HENG LONG NEW MATERIAL Co.,Ltd. (CN) 2021-06-22 CN disclosed
US-20210118637-A1 FLYING VEHICLE CURRENT INTERRUPTION DEVICE NIPPON KAYAKU KABUSHIKI KAISHA (JP) 2021-04-22 US disclosed
EP-0432941-B1 Polyolefin-substituted amines grafted with poly (aromatic-N-monomers) for oleaginous compositions EXXON CHEMICAL PATENTS INC (US) 1996-04-17 EP disclosed
US-5382632-A Ethylene-propylene-norbornene methylamine grafted with aniline EXXON CHEMICAL PATENTS INC. (US) 1995-01-17 US disclosed
US-5376728-A Oil-soluble, polyaniline-grafted addition polymers; electroconductivity; halogen-free; molding materials; thin films/electrical/ EXXON CHEMICAL PATENTS INC. (US) 1994-12-27 US disclosed
US-5278241-A Catalytic grafting of aromatic amines onto amino polymers EXXON CHEMICAL PATENTS INC. (US) 1994-01-11 US disclosed
US-5278240-A Catalytic grafting of aromatic amines onto amino polymers EXXON CHEMICAL PATENTS INC. (US) 1994-01-11 US disclosed
EP-0432939-A2 Oil soluble amino-substituted polymers containing graft polymer segments derived form aromatic nitrogen-containing monomers EXXON CHEMICAL PATENTS INC. (US) 1991-06-19 EP disclosed
EP-0432941-A2 Polyolefin-substituted amines grafted with poly (aromatic-N-monomers) for oleaginous compositions EXXON CHEMICAL PATENTS INC. (US) 1991-06-19 EP disclosed
US-4305823-A MODIFIED WITH CYCLIC B-KETONIC ACIDS CIBA-GEIGY CORPORATION (US) 1981-12-15 US disclosed
US-4249000-A SEMIPERMEABLE MEMBRANES FOR REVERSE OSMOSIS CIBA-GEIGY CORPORATION (US) 1981-02-03 US disclosed