Sugi Predict

Sugi Predict / Compounds / Butane

Butane

Butane

SCHEMBL6656493

CC(=O)OC(=O)CCC(=O)O.CCCC

nearest known ligand 0.48

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 3/20 0.48
▸ FFAR3 O14843 2/20 0.46
▸ HDAC3 O15379 1/20 0.46
▸ HDAC1 Q13547 1/20 0.46
▸ HDAC2 Q92769 1/20 0.46
▸ HDAC8 Q9BY41 1/20 0.46
▸ EGLN1 Q9GZT9 2/20 0.45
▸ KDM6B O15054 1/20 0.45
▸ KDM5C P41229 1/20 0.45
▸ PHF8 Q9UPP1 1/20 0.45
▸ KDM2A Q9Y2K7 1/20 0.45
▸ LMNA P02545 2/20 0.44
▸ SLC15A2 Q16348 1/20 0.44
▸ ALKBH5 Q6P6C2 1/20 0.41
▸ SUCNR1 Q9BXA5 1/20 0.41
▸ AKR1B1 P15121 1/20 0.41
▸ GPR84 Q9NQS5 7/20 0.39
▸ PPARG P37231 7/20 0.39
▸ PPARD Q03181 7/20 0.39
▸ PPARA Q07869 7/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propionic Acid SCHEMBL27721622 0.93 FFAR3 (0.48) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL1396840 0.93 EGLN1 (0.50) ALDH1A1FFAR3HDAC3HDAC1HDAC2
Butyric Acid SCHEMBL27701008 0.91 FFAR3 (0.59) ALDH1A1FFAR3HDAC3HDAC1HDAC2
Succinic Acid SCHEMBL27537735 0.91 ALDH1A1 (0.61) ALDH1A1FFAR3HDAC3HDAC1HDAC2
Ammonia Solution, Strong SCHEMBL16395684 0.91 EGLN1 (0.48) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL27750933 0.91 EGLN1 (0.48) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL8475243 0.91 EGLN1 (0.48) ALDH1A1FFAR3HDAC3HDAC1HDAC2
Butane SCHEMBL9015629 0.91 ALDH1A1 (0.57) ALDH1A1FFAR3HDAC3HDAC1HDAC2
Butane SCHEMBL5906885 0.88 ALDH1A1 (0.62) ALDH1A1FFAR3HDAC3HDAC1HDAC2
SCHEMBL27416649 0.86 PHF8 (0.45) ALDH1A1FFAR3HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114921776-A Chromium-free and fluorine-free film passivator for aluminum material and preparation and use method thereof 广州旭奇材料科技有限公司 2022-08-19 — — CN claimed
CN-118355459-A Conductive paste composition, method for producing conductive sheet, and method for producing electronic component 积水化学工业株式会社 2024-07-16 — — CN disclosed
US-11970448-B2 Monomers capable of dimerizing in an aqueous solution, and methods of using same CORNELL UNIVERSITY (US) 2024-04-30 — — US disclosed
WO-2023224010-A1 CONDUCTIVE PASTE COMPOSITION, MANUFACTURING METHOD FOR CONDUCTIVE SHEET, CONDUCTIVE SHEET, AND MANUFACTURING METHOD FOR ELECTRONIC COMPONENT 積水化学工業株式会社 2023-11-23 — — WO disclosed
US-20230339878-A1 SLC26A3 INHIBITORS AND USE THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2023-10-26 — — US disclosed
CN-116854776-A Fluorescent polypeptide probe and preparation method thereof 中国人民解放军陆军防化学院 2023-10-10 — — CN disclosed
EP-3319934-B1 PROCESS FOR THE ISOLATION OF LEVULINIC ACID GFBIOCHEMICALS IP ASSETS B V (NL) 2023-07-26 — — EP disclosed
CN-110172051-B IRE-1 alpha inhibitors 复星弘创(苏州)医药科技有限公司 2023-03-07 — — CN disclosed
US-11591304-B2 SLC26A3 inhibitors and use thereof THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-02-28 — — US disclosed
CN-114921776-A Chromium-free and fluorine-free film passivator for aluminum material and preparation and use method thereof 广州旭奇材料科技有限公司 2022-08-19 — — CN disclosed
WO-2013058824-A1 MONOMERS CAPABLE OF DIMERIZING IN AN AQUEOUS SOLUTION, AND METHODS OF USING SAME CORNELL UNIVERSITY (US) 2013-04-25 — — WO disclosed
WO-2012154213-A1 COFLUORONS AND METHODS OF MAKING AND USING THEM CORNELL UNIVERSITY (US) 2012-11-15 — — WO disclosed
EP-1479681-A1 IMIDAZO(1,2-a)PYRIDINE DERIVATIVE DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2004-11-24 — — EP disclosed
EP-0781276-B1 PYRIMIDINONE DERIVATIVES BORYUNG PHARM (KR) 2001-12-12 — — EP disclosed
US-6121055-A DETECTING COMPOUND IN SAMPLE; MIXING SAMPLE AND CHEMICAL INTERMEDIATE, SEPARATING INSOLUBLE COMPONENT OF MIXTURE, ADDING BINDING COMPONENT AND LABEL TO MIX, SEPARATE BINDING COMPONENT AND LABEL, DETECT BOUND LABEL AND BINDING COMPONENT ROCHE DIAGNOSTICS CORPORATION (US) 2000-09-19 — — US disclosed
US-5869476-A ANGIOTENSIN II ANTAGONISTS; TREATING CARDIOVASCULAR DISORDERS BORYUNG PHARMACEUTICAL CO., LTD. (KR) 1999-02-09 — — US disclosed
US-5073341-A Immunology, diagnosis BIOTOPE, INC. (US) 1991-12-17 — — US disclosed
EP-0344276-A1 METHODS AND DEVICES FOR CONDUCTING ASSAYS BOEHRINGER MANNHEIM CORPORATION (US) 1989-12-06 — — EP disclosed
US-4868130-A DENSITY SEPARATION BIOTOPE, INC. (US) 1989-09-19 — — US disclosed
US-3933798-A Novel bis-pyrazolone oxonol dyes POLAROID CORPORATION (US) 1976-01-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11970448-B2 Monomers capable of dimerizing in an aqueous solution, and methods of using same CALCOCO2, MDN1, MBNL1 ALDH1A1 4582/4885FFAR3 4375/4885HDAC3 4594/4885
US-20230339878-A1 SLC26A3 INHIBITORS AND USE THEREOF SLC26A3, SLC10A2, SLC10A6 ALDH1A1 2345/4885FFAR3 512/4885HDAC3 1445/4885
US-11591304-B2 SLC26A3 inhibitors and use thereof SLC26A3, SLC10A2, SLC10A6 ALDH1A1 2687/4885FFAR3 567/4885HDAC3 1462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.