Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.51 |
| ▸ | DGKA | P23743 | 1/20 | 0.69 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | PAM | P19021 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL125089 | 1.00 | DGKA (0.69) | DGKADNM1MAPTBLMRAD52 | |
| Hydrochloric Acid SCHEMBL243866 | 1.00 | DGKA (0.69) | DGKADNM1MAPTBLMRAD52 | |
| SCHEMBL7113105 | 0.98 | DGKA (0.71) | DGKADNM1MAPTBLMRAD52 | |
| SCHEMBL1049974 | 0.98 | DGKA (0.71) | DGKADNM1MAPTBLMRAD52 | |
| SCHEMBL7113175 | 0.98 | DGKA (0.71) | DGKADNM1MAPTBLMRAD52 | |
| SCHEMBL7114491 | 0.98 | DGKA (0.71) | DGKADNM1MAPTBLMRAD52 | |
| SCHEMBL377473 | 0.98 | DGKA (0.71) | DGKADNM1MAPTBLMRAD52 | |
| SCHEMBL1052058 | 0.98 | DGKA (0.71) | DGKADNM1MAPTBLMRAD52 | |
| SCHEMBL1056065 | 0.98 | DGKA (0.71) | DGKADNM1MAPTBLMRAD52 | |
| Hydrochloric Acid SCHEMBL3462945 | 0.97 | DGKA (0.65) | DGKADNM1MAPTBLMRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060058216-A1 | Concentrated, stable, preferably clear, fabric softening composition | TRINH TOAN | 2006-03-16 | — | — | US | disclosed |
| US-20060058215-A1 | Concentrated, stable, preferably clear, fabric softening composition | TRINH TOAN | 2006-03-16 | — | — | US | disclosed |
| EP-1352948-A1 | Concentrated, stable, fabric softening composition | THE PROCTER & GAMBLE COMPANY (US) | 2003-10-15 | — | — | EP | disclosed |
| US-20030153483-A1 | Concentrated, stable fabric softening composition | TRINH TOAN (US) | 2003-08-14 | — | — | US | disclosed |
| US-6369025-B1 | USEFUL FOR SOFTENING CLOTH | THE PROCTER & GAMBLE COMPANY | 2002-04-09 | — | — | US | disclosed |
| US-6323172-B1 | AQUEOUS COMPOSITION COMPRISING FABRIC SOFTENER, SELECTED PRINCIPAL SOLVENT, LOW MOLECULAR WEIGHT WATER SOLUBLE SOLVENT TO IMPROVE CLARITY, WATER SOLUBLE CALCIUM AND/OR MAGNESIUM SALT | THE PROCTER & GAMBLE COMPANY | 2001-11-27 | — | — | US | disclosed |
| EP-0918842-A1 | SUBSTANTIALLY ODOR-FREE POLYHYDROXYL SOLVENTS | THE PROCTER & GAMBLE COMPANY (US) | 1999-06-02 | — | — | EP | disclosed |
| EP-0839179-A1 | CONCENTRATED, WATER DISPERSIBLE, STABLE, FABRIC SOFTENING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1998-05-06 | — | — | EP | disclosed |
| WO-1998002513-A1 | SUBSTANTIALLY ODOR-FREE POLYHYDROXYL SOLVENTS | THE PROCTER & GAMBLE COMPANY (US) | 1998-01-22 | — | — | WO | disclosed |
| WO-1997003170-A1 | CONCENTRATED, WATER DISPERSIBLE, STABLE, FABRIC SOFTENING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1997-01-30 | — | — | WO | disclosed |