Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.51 |
| ▸ | DGKA | P23743 | 1/20 | 0.69 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | RAD52 | P43351 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | PAM | P19021 | 2/20 | 0.53 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.50 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5907091 | 1.00 | DGKA (0.69) | DGKADNM1MAPTBLMRAD52 | |
| Hydrochloric Acid SCHEMBL243866 | 1.00 | DGKA (0.69) | DGKADNM1MAPTBLMRAD52 | |
| SCHEMBL7113105 | 0.98 | DGKA (0.71) | DGKADNM1MAPTBLMRAD52 | |
| SCHEMBL1049974 | 0.98 | DGKA (0.71) | DGKADNM1MAPTBLMRAD52 | |
| SCHEMBL7113175 | 0.98 | DGKA (0.71) | DGKADNM1MAPTBLMRAD52 | |
| SCHEMBL7114491 | 0.98 | DGKA (0.71) | DGKADNM1MAPTBLMRAD52 | |
| SCHEMBL377473 | 0.98 | DGKA (0.71) | DGKADNM1MAPTBLMRAD52 | |
| SCHEMBL1052058 | 0.98 | DGKA (0.71) | DGKADNM1MAPTBLMRAD52 | |
| SCHEMBL1056065 | 0.98 | DGKA (0.71) | DGKADNM1MAPTBLMRAD52 | |
| Hydrochloric Acid SCHEMBL3462945 | 0.97 | DGKA (0.65) | DGKADNM1MAPTBLMRAD52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119486702-A | Organic ultraviolet blocker capsule having ultraviolet blocking efficiency improving effect | 株式会社LG生活健康 | 2025-02-18 | — | — | CN | claimed |
| US-11883514-B2 | Stable low pH personal care compositions and methods for the same | COLGATE-PALMOLIVE COMPANY (US) | 2024-01-30 | — | — | US | claimed |
| WO-2023239201-A1 | ORGANIC SUNSCREEN CAPSULE HAVING UV PROTECTION EFFICIENCY INCREASING EFFECT | 주식회사 엘지생활건강 | 2023-12-14 | — | — | WO | claimed |
| WO-2026104110-A1 | FOAM CONDITIONER | HENKEL AG & CO. KGAA (DE) | 2026-05-21 | — | — | WO | disclosed |
| WO-2026098867-A1 | OXIDATIVE HAIR BRIGHTENING BY MEANS OF PERSULFATE, DICARBOXYLIC ACID, AND CITRULLINE | HENKEL AG & CO. KGAA (DE) | 2026-05-15 | — | — | WO | disclosed |
| US-12622856-B2 | Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer | HENKEL AG & CO. KGAA (DE) | 2026-05-12 | — | — | US | disclosed |
| WO-2025131884-A1 | OIL-IN-WATER EMULSION WITH WIDE RANGE OF APPLICATIONS, FOR OXIDATIVELY CHANGING THE COLOUR OF KERATIN FIBRES | HENKEL AG & CO. KGAA (DE) | 2025-06-26 | — | — | WO | disclosed |
| WO-2025119816-A1 | BLEACHING AGENTS CONTAINING VANILLIN ADDITIVE | HENKEL AG & CO. KGAA (DE) | 2025-06-12 | — | — | WO | disclosed |
| US-20250152484-A1 | OIL-IN-WATER EMULSION SKIN PREPARATION FOR EXTERNAL USE | KAO CORPORATION (JP) | 2025-05-15 | — | — | US | disclosed |
| US-20250073155-A1 | HAIR CONDITIONER FOR STRAIGHTENING HAIR | HENKEL AG & CO KGAA (DE) | 2025-03-06 | — | — | US | disclosed |
| EP-4514306-A1 | OXIDATIVE HAIR-LIGHTENING AGENTS HAVING IMPROVED APPLICATION PROPERTIES FOR BLEACHING HAIR ROOTS | Henkel AG & Co. KGaA (DE) | 2025-03-05 | — | — | EP | disclosed |
| WO-2001010399-A1 | METHOD FOR DYEING FIBRES CONTAINING KERATIN | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2001-02-15 | — | — | WO | disclosed |
| WO-2000061066-A2 | COSMETIC PRODUCT AND ITS USE | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 2000-10-19 | — | — | WO | disclosed |
| EP-1037589-A1 | AGENTS FOR TREATING KERATIN FIBRES | Hans Schwarzkopf GmbH & Co. KG (DE) | 2000-09-27 | — | — | EP | disclosed |
| WO-2000049999-A1 | PREPARATIONS FOR TREATING KERATIN FIBRES | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 2000-08-31 | — | — | WO | disclosed |
| WO-2000050000-A1 | PREPARATIONS FOR TREATING KERATIN FIBRES | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 2000-08-31 | — | — | WO | disclosed |
| EP-1009367-A2 | USE OF A COMBINATION OF ACTIVE SUBSTANCES AND AGENT FOR PROTECTING KERATINIC FIBERS | Hans Schwarzkopf GmbH & Co. KG (DE) | 2000-06-21 | — | — | EP | disclosed |
| WO-1999030673-A1 | AGENTS FOR TREATING KERATIN FIBRES | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 1999-06-24 | — | — | WO | disclosed |
| WO-1999011224-A2 | USE OF A COMBINATION OF ACTIVE SUBSTANCES AND AGENT FOR THE PROTECTION OF KERATIN FIBRES | HANS SCHWARZKOPF GMBH & CO. KG (DE) | 1999-03-11 | — | — | WO | disclosed |
| CN-1121352-A | Concentrated biodegradable quaternary ammonium fabric softener compositions and compounds containing unsaturated fatty acid chains of moderate iodine value | PROCTER & GAMBLE (US) | 1996-04-24 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12622856-B2 | Agent for oxidative dyeing of keratin fibers, containing isatin and at least one defined polymer | KRT18, ARSA, MKI67 | ACHE 653/4885DGKA 3121/4885DNM1 4857/4885 |
| US-20250152484-A1 | OIL-IN-WATER EMULSION SKIN PREPARATION FOR EXTERNAL USE | CUTA, NAPEPLD, LIPA | ACHE 2599/4885DGKA 107/4885DNM1 3557/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.