Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTAFR known ✓ | P25105 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2C | P28335 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 3/20 | 0.31 |
| ▸ | CETP | P11597 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27636305 | 0.72 | NR3C1 (0.32) | CA12CA1CA2CA4CA7 | |
| Hydrochloric Acid SCHEMBL28066485 | 0.72 | NR3C1 (0.32) | CA12CA1CA2CA4CA7 | |
| SCHEMBL17014295 | 0.71 | NR3C1 (0.38) | CA12CA1CA2CA4CA7 | |
| Hydrochloric Acid SCHEMBL29911832 | 0.70 | NR3C1 (0.32) | NR3C1ADRA1A | |
| Hydrochloric Acid SCHEMBL7553845 | 0.70 | NR3C1 (0.32) | NR3C1ADRA1A | |
| Hydrochloric Acid SCHEMBL6356342 | 0.70 | ADRA1A (0.35) | ADRA1AHTR2AHTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL4004708 | 0.70 | ADRA1A (0.32) | ADRA1A | |
| SCHEMBL27282348 | 0.69 | NR3C1 (0.33) | CA12CA1CA2CA4CA7 | |
| SCHEMBL28331513 | 0.69 | NR3C1 (0.33) | CA12CA1CA2CA4CA7 | |
| Hydrochloric Acid SCHEMBL9440762 | 0.68 | NR3C1 (0.32) | CA12CA1CA2CA4CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469701-B2 | Polyethylene powder | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-10-18 | — | — | US | disclosed |
| US-20160137760-A1 | Polyethylene Powder | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2016-05-19 | — | — | US | disclosed |
| US-20060287449-A1 | Ultrahigh-molecular ethylene polymer | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2006-12-21 | — | — | US | disclosed |
| EP-1605000-A1 | ULTRAHIGH-MOLECULAR ETHYLENE POLYMER | Asahi Kasei Chemicals Corporation (JP) | 2005-12-14 | — | — | EP | disclosed |