Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 8/20 | 0.69 |
| ▸ | CHRNA4 | P43681 | 8/20 | 0.69 |
| ▸ | CHRNA7 | P36544 | 7/20 | 0.63 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.45 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.45 |
| ▸ | CHRNG | P07510 | 1/20 | 0.45 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.45 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.45 |
| ▸ | CHRND | Q07001 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29411316 | 1.00 | CHRNB2 (0.69) | CHRNB2CHRNA4CHRNA7CYP2A6MEN1 | |
| SCHEMBL30711273 | 0.85 | CHRNB2 (0.51) | CHRNB2CHRNA4CHRNA7CYP2A6MEN1 | |
| SCHEMBL16272028 | 0.85 | CHRNB2 (0.62) | CHRNB2CHRNA4CHRNA7CYP2A6MEN1 | |
| Hydrochloric Acid SCHEMBL17667438 | 0.84 | CHRNB2 (0.60) | CHRNB2CHRNA4CHRNA7CYP2A6MEN1 | |
| Hydrochloric Acid SCHEMBL27806813 | 0.83 | CHRNB2 (0.58) | CHRNB2CHRNA4CHRNA7CYP2A6MEN1 | |
| SCHEMBL159642 | 0.82 | CHRNB2 (1.00) | CHRNB2CHRNA4CHRNA7CYP2A6MEN1 | |
| SCHEMBL7008708 | 0.82 | CHRNB2 (0.67) | CHRNB2CHRNA4CHRNA7CYP2A6MEN1 | |
| SCHEMBL31465048 | 0.82 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNA7CYP2A6MEN1 | |
| SCHEMBL30676152 | 0.79 | CYP11B2 (0.67) | CHRNB2CHRNA4CHRNA7CYP2A6MEN1 | |
| SCHEMBL533875 | 0.79 | CYP11B2 (0.67) | CHRNB2CHRNA4CHRNA7CYP2A6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060041962-A1 | Genes and uses thereof to modulate secondary metabolite biosynthesis | VALTION TEKNILLINEN TUTKIMUSKESKUS (VTT) (FI) | 2006-02-23 | — | — | US | disclosed |
| EP-1506300-A2 | GENES AND USES THEREOF TO MODULATE SECONDARY METABOLITE BIOSYNTHESIS | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. (BE) | 2005-02-16 | — | — | EP | disclosed |
| WO-2003097790-A2 | GENES AND USES THEREOF TO MODULATE SECONDARY METABOLITE BIOSYNTHESIS | VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW (BE) | 2003-11-27 | — | — | WO | disclosed |