Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 5/20 | 0.51 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.41 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30711285 | 0.87 | HCAR2 (0.39) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| SCHEMBL30711227 | 0.86 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| SCHEMBL31465048 | 0.86 | CHRNB2 (0.47) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| SCHEMBL30711259 | 0.86 | AKR1C3 (0.44) | CYP2D6 | |
| SCHEMBL5912286 | 0.85 | CHRNB2 (0.69) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| SCHEMBL29411316 | 0.85 | CHRNB2 (0.69) | CHRNB2CHRNA4CHRNA7MEN1CYP2D6 | |
| SCHEMBL30711292 | 0.85 | P2RY14 (0.42) | MEN1CYP2D6KMT2AALDH1A1KDM4E | |
| SCHEMBL30711375 | 0.84 | HCAR2 (0.40) | CHRNB2CHRNA4CHRNA7CYP2D6KMT2A | |
| SCHEMBL30711374 | 0.81 | SLC6A7 (0.35) | KMT2ASMN1; SMN2ALDH1A1HCAR3L3MBTL1 | |
| SCHEMBL30711200 | 0.80 | KDM5A (0.34) | CHRNB2CHRNA4CHRNA7CYP2D6MKNK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023246677-A1 | INDOLE-PHENYLPIPERIDINE COMPOUND, METHOD FOR PREPARING SAME, AND USE THEREOF | 深圳信立泰药业股份有限公司 | 2023-12-28 | — | — | WO | disclosed |