Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | PDE6D | O43924 | 1/20 | 0.50 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.50 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.50 |
| ▸ | TLR7 | Q9NYK1 | 7/20 | 0.49 |
| ▸ | BCL2 | P10415 | 1/20 | 0.48 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5914423 | 0.93 | ALDH1A1 (0.56) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL5914226 | 0.74 | PDE4A (0.55) | TLR7 | |
| SCHEMBL30984055 | 0.73 | KMT2A (0.48) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL11156722 | 0.71 | ALDH1A1 (0.54) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL30898278 | 0.70 | YTHDC1 (0.68) | ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL11153474 | 0.70 | ALDH1A1 (0.53) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL183057 | 0.70 | YTHDC1 (0.68) | ALDH1A1CYP1A2CYP2C9CYP2C19 | |
| SCHEMBL18152641 | 0.70 | HTR6 (0.48) | ALDH1A1KDM4EHPGDRAB9ATLR7 | |
| SCHEMBL11160756 | 0.69 | ALDH1A1 (0.51) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 | |
| SCHEMBL29829358 | 0.69 | ALDH1A1 (0.63) | ALDH1A1KDM4EHPGDLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060234974-A1 | 2,6-Dihalogeno-8-substituent-purine compound and process for producing the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2006-10-19 | — | — | US | disclosed |
| EP-1595882-A1 | 2,6-DIHALOGENO-8-SUBSTITUENT-PURINE COMPOUND AND PROCESS FOR PRODUCING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2005-11-16 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060234974-A1 | 2,6-Dihalogeno-8-substituent-purine compound and process for producing the same | HPRT1, TPMT, NUDT1 | ALDH1A1 536/4885KDM4E 2871/4885HPGD 659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.