Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 8/20 | 0.53 |
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | CXCL12 | P48061 | 2/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5915572 | 1.00 | LMNA (0.58) | LMNAALDH1A1KDM4EPKMMAPT | |
| SCHEMBL1225557 | 0.89 | LMNA (0.65) | LMNAALDH1A1KDM4EPKMMAPT | |
| SCHEMBL1225556 | 0.89 | LMNA (0.65) | LMNAALDH1A1KDM4EPKMMAPT | |
| Bromide SCHEMBL11834524 | 0.88 | LMNA (0.63) | LMNAALDH1A1KDM4EPKMMAPT | |
| Bromide SCHEMBL11834530 | 0.88 | LMNA (0.63) | LMNAALDH1A1KDM4EPKMMAPT | |
| SCHEMBL29406300 | 0.85 | MAPT (0.68) | LMNAALDH1A1KDM4EPKMMAPT | |
| SCHEMBL3064890 | 0.85 | MAPT (0.68) | LMNAALDH1A1KDM4EPKMMAPT | |
| SCHEMBL3064887 | 0.85 | MAPT (0.68) | LMNAALDH1A1KDM4EPKMMAPT | |
| SCHEMBL5915537 | 0.85 | LMNA (0.61) | LMNAALDH1A1KDM4EPKMMAPT | |
| SCHEMBL5915544 | 0.85 | LMNA (0.61) | LMNAALDH1A1KDM4EPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060052600-A1 | Amino-functional chalcones | LICA PHARMACEUTICALS A/S (DK) | 2006-03-09 | — | — | US | disclosed |