Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 4/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5922054 | 0.83 | HPGD (0.36) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL11557945 | 0.78 | HPGD (0.62) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL5922102 | 0.78 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL5731937 | 0.72 | L3MBTL1 (0.53) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL3749553 | 0.70 | ALDH1A1 (1.00) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL1472457 | 0.70 | ALDH1A1 (0.62) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL5643443 | 0.68 | HPGD (0.78) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL4734710 | 0.68 | KMT2A (0.78) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL5362218 | 0.68 | HPGD (1.00) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL2739332 | 0.68 | PTGS2 (0.74) | ALDH1A1HPGDKDM4EKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060270656-A1 | Substituted piperazines of azepines, oxazepines and thiazepines | ELI LILLY AND COMPANY | 2006-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060270656-A1 | Substituted piperazines of azepines, oxazepines and thiazepines | HRH4, HRH2, HRH3 | ALDH1A1 2523/4885HPGD 3357/4885KDM4E 2816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.