Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | PLAAT3 | P53816 | 3/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 3/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 3/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 3/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | LTA4H | P09960 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.42 |
| ▸ | RELA | Q04206 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5923119 | 0.94 | HTT (0.48) | EPHX2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5923376 | 0.86 | EPHX2 (0.49) | EPHX2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5923231 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1LMNAALOX12TP53GLA | |
| SCHEMBL5923285 | 0.80 | EPHX2 (0.46) | EPHX2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5923299 | 0.79 | EPHX2 (0.46) | EPHX2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5923323 | 0.77 | EPHX2 (0.43) | EPHX2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL6511300 | 0.76 | ADORA2A (0.64) | ALDH1A1LMNATP53GLAMAPT | |
| SCHEMBL5923332 | 0.76 | EPHX2 (0.49) | EPHX2PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL5923352 | 0.76 | HTT (0.47) | ALDH1A1LMNATP53GLAMAPT | |
| SCHEMBL5923099 | 0.76 | MITF (0.47) | ALDH1A1LMNATP53GLAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060100225-A1 | Heteroaryl guanidines; inhibitors of viral replication | ACHILLION PHARMACEUTICALS, INC. | 2006-05-11 | — | — | US | claimed |
| WO-2005095345-A2 | HETEROARYL GUANIDINES AS INHIBITORS OF VIRAL REPLICATION | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | claimed |
| US-20060100225-A1 | Heteroaryl guanidines; inhibitors of viral replication | ACHILLION PHARMACEUTICALS, INC. | 2006-05-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060100225-A1 | Heteroaryl guanidines; inhibitors of viral replication | PIGS, GUCY1A1, GUCY1B1 | EPHX2 3096/4885PLAAT3 993/4885PLAAT5 2045/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.