Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.86 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.86 |
| ▸ | PDE4A | P27815 | 1/20 | 0.65 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.65 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5923929 | 1.00 | TAS1R3 (0.86) | TAS1R3TAS1R1PDE4APDE4BPDE4C | |
| SCHEMBL702688 | 0.93 | TAS1R3 (1.00) | TAS1R3TAS1R1LMNAHTTTAS1R2 | |
| SCHEMBL5923966 | 0.90 | TAS1R3 (0.70) | TAS1R3TAS1R1PDE4APDE4BPDE4C | |
| SCHEMBL5923964 | 0.90 | TAS1R3 (0.70) | TAS1R3TAS1R1PDE4APDE4BPDE4C | |
| SCHEMBL5923976 | 0.84 | PDE4A (0.83) | TAS1R3TAS1R1PDE4APDE4BPDE4C | |
| SCHEMBL2064346 | 0.84 | PDE4A (0.83) | TAS1R3TAS1R1PDE4APDE4BPDE4C | |
| SCHEMBL2064349 | 0.84 | PDE4A (0.83) | TAS1R3TAS1R1PDE4APDE4BPDE4C | |
| SCHEMBL5969951 | 0.83 | NPC1 (0.70) | TAS1R3TAS1R1PDE4APDE4BPDE4C | |
| SCHEMBL5923926 | 0.82 | TAS1R3 (0.61) | TAS1R3TAS1R1PDE4APDE4BPDE4C | |
| SCHEMBL20067635 | 0.82 | LMNA (0.86) | TAS1R3TAS1R1PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |