SCHEMBL592575

SCHEMBL592575

C=CCCCCO[Si](C)(C)C(C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.38
LPAR3 Q9UBY5 2/20 0.37
LPAR2 Q9HBW0 1/20 0.37
DUT P33316 2/20 0.36
ALDH1A1 P00352 2/20 0.36
LMNA P02545 1/20 0.33
SLC2A1 P11166 1/20 0.32
CDK1 P06493 1/20 0.30
CCNB1 P14635 1/20 0.30
CCNA2 P20248 1/20 0.30
CDK2 P24941 1/20 0.30
CCNA1 P78396 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1931760 0.98 TSHR (0.41) TSHRLPAR3LPAR2DUTALDH1A1
SCHEMBL17732227 0.98 TSHR (0.41) TSHRLPAR3LPAR2DUTALDH1A1
SCHEMBL2245848 0.98 TSHR (0.41) TSHRLPAR3LPAR2DUTALDH1A1
SCHEMBL30895945 0.98 TSHR (0.41) TSHRLPAR3LPAR2DUTALDH1A1
SCHEMBL4455945 0.94 DUT (0.37) TSHRLPAR3LPAR2DUTALDH1A1
SCHEMBL2244296 0.91 TSHR (0.36) TSHRLPAR3LPAR2DUTALDH1A1
SCHEMBL25242422 0.85 USP2 (0.43) TSHRLPAR3LPAR2DUTALDH1A1
SCHEMBL25239911 0.85 USP2 (0.43) TSHRLPAR3LPAR2DUTALDH1A1
SCHEMBL25239118 0.85 ALDH1A1 (0.46) TSHRLPAR3LPAR2DUTALDH1A1
SCHEMBL4059577 0.85 DUT (0.33) TSHRDUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4484457-B1 HOT MELT ADHESIVES BASED ON BLENDS COMPRISING NON-FUNCTIONALIZED AND FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-06-25 EP claimed
EP-4484516-B1 HOT MELT ADHESIVES BASED ON BLENDS COMPRISING NON-FUNCTIONALIZED AND FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-06-25 EP claimed
CN-119948125-A Hot melt adhesive comprising siloxy functionalized polyolefin SABIC环球技术有限责任公司 2025-05-06 CN claimed
WO-2025002626-A1 HOT MELT ADHESIVES BASED ON BLENDS COMPRISING NON- FUNCTIONALIZED AND FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-01-02 WO claimed
WO-2025002627-A1 HOT MELT ADHESIVES BASED ON BLENDS COMPRISING NON-FUNCTIONALIZED AND FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2025-01-02 WO claimed
EP-4484516-A1 HOT MELT ADHESIVES BASED ON BLENDS COMPRISING NON-FUNCTIONALIZED AND FUNCTIONALIZED POLYOLEFINS SABIC Global Technologies B.V. (NL) 2025-01-01 EP claimed
EP-4484457-A1 HOT MELT ADHESIVES BASED ON BLENDS COMPRISING NON-FUNCTIONALIZED AND FUNCTIONALIZED POLYOLEFINS SABIC Global Technologies B.V. (NL) 2025-01-01 EP claimed
EP-4702000-A1 ALKYLATION PROCESS University of Liverpool (GB) 2026-03-04 EP disclosed
EP-4608926-A1 HOT MELT ADHESIVE COMPRISING SILOXIDE-FUNCTIONALIZED POLYOLEFINS SABIC Global Technologies B.V. (NL) 2025-09-03 EP disclosed
EP-4484516-B1 HOT MELT ADHESIVES BASED ON BLENDS COMPRISING NON-FUNCTIONALIZED AND FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-06-25 EP disclosed
EP-4484457-B1 HOT MELT ADHESIVES BASED ON BLENDS COMPRISING NON-FUNCTIONALIZED AND FUNCTIONALIZED POLYOLEFINS SABIC GLOBAL TECHNOLOGIES BV (NL) 2025-06-25 EP disclosed
CN-116199806-B Coordination precipitation polymerization method for olefin polymerization and obtained polyolefin 中国石油化工股份有限公司 2025-05-06 CN disclosed
CN-119948125-A Hot melt adhesive comprising siloxy functionalized polyolefin SABIC环球技术有限责任公司 2025-05-06 CN disclosed
CN-1203847-C Chemically defined non-polymeric valency platform molecules and conjugates thereof JOLLA PHARMA (US) 2005-06-01 CN disclosed
CN-1572797-A Chemically-defined non-polymeric valency platform molecules and conjugates thereof JOLLA PHARMACEUT CO (US) 2005-02-02 CN disclosed
US-5874552-A Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides LA JOLLA PHARMACEUTICAL COMPANY (US) 1999-02-23 US disclosed
US-5786512-A Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides LAJOLLA PHARMACEUTICAL COMPANY (US) 1998-07-28 US disclosed
US-5726329-A Modified phosphorous intermediates for providing functional groups on the 5' end of oligonucleotides LA JOLLA PHARMACEUTICAL COMPANY (US) 1998-03-10 US disclosed
CN-1134109-A Chemically defined non-polymeric valency platform molecules and conjugates thereof JOLLA PHARMA (US) 1996-10-23 CN disclosed
US-5391785-A Intermediates for providing functional groups on the 5' end of oligonucleotides LA JOLLA PHARMACEUTIAL COMPANY (US) 1995-02-21 US disclosed