Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIFC1 | Q9BW19 | 8/20 | 0.53 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.51 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5926596 | 0.88 | CTSA (0.42) | KIFC1GPR34MAPK14RXFP1 | |
| SCHEMBL5926244 | 0.88 | GPR34 (0.49) | KIFC1GPR34MCL1ITGB1ITGA4 | |
| SCHEMBL5927135 | 0.87 | PDK1 (0.46) | GPR34MCL1ITGB1ITGA4PDK1 | |
| SCHEMBL5927459 | 0.87 | PDK1 (0.46) | KIFC1GPR34MCL1ITGB1ITGA4 | |
| SCHEMBL5926729 | 0.86 | KMT2A (0.44) | KIFC1ITGB1ITGA4KMT2APPARG | |
| SCHEMBL5926340 | 0.86 | KMT2A (0.44) | KIFC1GPR34ITGB1ITGA4PDK1 | |
| SCHEMBL5926379 | 0.85 | KIFC1 (0.51) | KIFC1GPR34MCL1ITGB1ITGA4 | |
| SCHEMBL5927334 | 0.83 | PDK1 (0.44) | KIFC1GPR34MCL1ITGB1ITGA4 | |
| SCHEMBL4832849 | 0.80 | KIFC1 (0.62) | KIFC1GPR34MCL1ITGB1ITGA4 | |
| SCHEMBL4831832 | 0.80 | KIFC1 (0.62) | KIFC1GPR34MCL1ITGB1ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. | 2006-12-07 | — | — | US | disclosed |
| US-7122580-B2 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. (US) | 2006-10-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TFPI, F9, F2 | KIFC1 4489/4885GPR34 4272/4885MCL1 3495/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.