Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.54 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.54 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.54 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.54 |
| ▸ | KIFC1 | Q9BW19 | 5/20 | 0.54 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.52 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.52 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.52 |
| ▸ | ECE1 | P42892 | 2/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.49 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | FPR2 | P25090 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5926920 | 0.91 | PDK1 (0.56) | PDK1PDK2PDK3PDK4KIFC1 | |
| SCHEMBL3994928 | 0.91 | ITGB1 (0.61) | PDK1PDK2PDK3PDK4ITGB1 | |
| SCHEMBL4829787 | 0.89 | ITGB1 (0.51) | PDK1PDK2PDK3PDK4KIFC1 | |
| SCHEMBL3989525 | 0.89 | ITGB1 (0.51) | PDK1PDK2PDK3PDK4KIFC1 | |
| SCHEMBL6097133 | 0.89 | ITGB1 (0.51) | PDK1PDK2PDK3PDK4KIFC1 | |
| SCHEMBL3991301 | 0.89 | ITGB1 (0.51) | PDK1PDK2PDK3PDK4KIFC1 | |
| SCHEMBL5927385 | 0.89 | CA2 (0.62) | PDK1PDK2PDK3PDK4KIFC1 | |
| SCHEMBL4827755 | 0.86 | KIFC1 (0.51) | KIFC1ITGB1ITGA4MRGPRX4ECE1 | |
| SCHEMBL4827753 | 0.86 | KIFC1 (0.51) | KIFC1ITGB1ITGA4MRGPRX4ECE1 | |
| SCHEMBL5926493 | 0.85 | PTPN1 (0.62) | PDK1PDK2PDK3PDK4KIFC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TRANSTECH PHARMA, INC. | 2006-12-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060276518-A1 | Aryl and heteroaryl compounds and methods to modulate coagulation | TFPI, F9, F2 | PDK1 2955/4885PDK2 2541/4885PDK3 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.