Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | NR3C2 | P08235 | 2/20 | 0.39 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5892020 | 0.81 | CES1 (0.46) | CES1SRCHTTSMN1; SMN2 | |
| SCHEMBL1395461 | 0.79 | CES1 (0.50) | CES1SRCKMT2AKCNN4SMN1; SMN2 | |
| SCHEMBL754131 | 0.76 | CES1 (0.47) | CES1SRCKCNN4SMN1; SMN2ALDH1A1 | |
| SCHEMBL5483963 | 0.75 | CES1 (0.46) | CES1SRCKMT2AKCNN4SMN1; SMN2 | |
| SCHEMBL1252890 | 0.75 | CES1 (0.46) | CES1SRCKMT2AKCNN4SMN1; SMN2 | |
| SCHEMBL4769359 | 0.75 | KCNN4 (0.48) | CES1SRCKMT2AKCNN4HTT | |
| SCHEMBL3631032 | 0.74 | CES1 (0.49) | CES1SRCKMT2AKCNN4HTT | |
| SCHEMBL11057570 | 0.73 | CES1 (0.45) | CES1SRCKMT2AKCNN4HTT | |
| SCHEMBL6150376 | 0.73 | SRC (0.52) | CES1SRCKMT2ANR3C2SMN1; SMN2 | |
| SCHEMBL5843722 | 0.72 | ALDH1A1 (0.44) | CES1SRCKMT2AKCNN4HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060211740-A1 | Novel compounds | GLAXO GROUP LIMITED | 2006-09-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060211740-A1 | Novel compounds | BACE2, BACE1, PSEN2 | CES1 1417/4885SRC 4533/4885KMT2A 590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.