Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 2/20 | 0.48 |
| ▸ | CES1 | P23141 | 5/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6929453 | 0.84 | KCNN4 (0.53) | KCNN4ALDH1A1LMNAHTTL3MBTL1 | |
| SCHEMBL1395461 | 0.80 | CES1 (0.50) | KCNN4CES1SRCALDH1A1LMNA | |
| SCHEMBL6443992 | 0.79 | ALDH1A1 (0.45) | CES1SRCALDH1A1LMNAHTT | |
| SCHEMBL754131 | 0.77 | CES1 (0.47) | KCNN4CES1SRCALDH1A1L3MBTL1 | |
| SCHEMBL10384239 | 0.77 | CES1 (0.50) | KCNN4CES1SRCLMNAMEN1 | |
| SCHEMBL5483963 | 0.77 | CES1 (0.46) | KCNN4CES1SRCALDH1A1L3MBTL1 | |
| SCHEMBL1252890 | 0.77 | CES1 (0.46) | KCNN4CES1SRCALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL19305003 | 0.75 | CES1 (0.48) | KCNN4CES1SRCLMNAMEN1 | |
| SCHEMBL5928512 | 0.75 | CES1 (0.45) | KCNN4CES1SRCALDH1A1HTT | |
| SCHEMBL390943 | 0.74 | CES1 (0.52) | CES1SRCALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007834-A1 | SULPHONIUM SALT INITIATORS | Ciba Holding Inc. (CH) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118794-A1 | SULPHONIUM SALT INITIATORS | CIBA HOLDING INC. (CH) | 2007-10-25 | — | — | WO | disclosed |