Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.48 |
| ▸ | NPY1R | P25929 | 1/20 | 0.48 |
| ▸ | NPY2R | P49146 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5928922 | 0.87 | LMNA (0.70) | LMNAHTTPDE4DTP53NPY1R | |
| SCHEMBL9593922 | 0.77 | LMNA (0.67) | LMNAHTTTP53NPY1RNPY2R | |
| SCHEMBL5928906 | 0.77 | KMT2A (0.52) | LMNAHTTHPGDALDH1A1MEN1 | |
| SCHEMBL5928767 | 0.77 | KMT2A (0.52) | LMNAHTTHPGDALDH1A1MEN1 | |
| SCHEMBL11487535 | 0.76 | LMNA (0.74) | LMNAHTTHPGDALDH1A1MEN1 | |
| SCHEMBL8952208 | 0.74 | HPGD (0.47) | PDE4DTP53HPGDALDH1A1MEN1 | |
| SCHEMBL23410754 | 0.71 | MALT1 (0.50) | LMNATP53HPGDALDH1A1KDM4E | |
| SCHEMBL13975145 | 0.71 | LMNA (0.57) | LMNAPDE4DHPGDALDH1A1MEN1 | |
| SCHEMBL8883561 | 0.70 | LMNA (0.60) | LMNAHTTTP53ALDH1A1MEN1 | |
| SCHEMBL1779819 | 0.70 | HTT (0.64) | LMNAHTTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060229324-A1 | Quinazolin-4-one derivatives | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2006-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060229324-A1 | Quinazolin-4-one derivatives | HPGDS, PTGS1, PTGDR | LMNA 3667/4885HTT 4273/4885PDE4D 1155/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.