Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.45 |
| ▸ | NPY2R | P49146 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11487535 | 0.82 | LMNA (0.74) | LMNAALDH1A1HPGDHTTMAPT | |
| SCHEMBL5928922 | 0.80 | LMNA (0.70) | LMNAALDH1A1HTTMAPTPOLB | |
| Acetic Acid SCHEMBL9593918 | 0.78 | LMNA (0.56) | LMNAALDH1A1HPGDHTTMAPT | |
| SCHEMBL5928913 | 0.77 | LMNA (0.58) | LMNAALDH1A1HPGDHTTMAPT | |
| SCHEMBL8883561 | 0.76 | LMNA (0.60) | LMNAALDH1A1HTTMAPTPOLB | |
| SCHEMBL1779819 | 0.76 | HTT (0.64) | LMNAALDH1A1HTTMAPTPOLB | |
| SCHEMBL29956682 | 0.73 | LMNA (0.60) | LMNAALDH1A1HTTMAPTPOLB | |
| SCHEMBL1267498 | 0.73 | SMN1; SMN2 (0.66) | LMNAALDH1A1HPGDHTTMAPT | |
| SCHEMBL3835167 | 0.73 | HTT (0.64) | LMNAALDH1A1HTTMAPTPOLB | |
| SCHEMBL8883850 | 0.73 | LMNA (0.60) | LMNAALDH1A1HTTMAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5240947-A | Thrombocyte aggregation inhibitors, antiallergens | NATIONAL SCIENCE COUNCIL (TW) | 1993-08-31 | — | — | US | disclosed |