Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28861954 | 0.70 | SIGMAR1 (0.39) | SIGMAR1ALDH1A1 | |
| SCHEMBL5932021 | 0.68 | CHRM1 (0.38) | SIGMAR1CHRM1ALDH1A1 | |
| SCHEMBL4726231 | 0.67 | SIGMAR1 (0.39) | SIGMAR1ALDH1A1 | |
| SCHEMBL21516061 | 0.67 | LMNA (0.41) | SIGMAR1ALDH1A1 | |
| SCHEMBL7940102 | 0.64 | GSK3A (0.37) | SIGMAR1ALDH1A1 | |
| SCHEMBL6663998 | 0.62 | KDM4E (0.35) | SIGMAR1ALDH1A1 | |
| SCHEMBL29558359 | 0.61 | MAOA (0.41) | SIGMAR1 | |
| SCHEMBL6615747 | 0.60 | GSK3A (0.43) | SIGMAR1ALDH1A1 | |
| SCHEMBL5668049 | 0.59 | SIGMAR1 (0.41) | SIGMAR1ALDH1A1 | |
| SCHEMBL30763535 | 0.59 | SIGMAR1 (0.31) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060241097-A1 | Pesticidal substituted 1,2,5-thiadiazole derivatives | FMC CORPORATION (US) | 2006-10-26 | — | — | US | disclosed |
| WO-2005006858-A2 | PESTICIDAL SUBSTITUTED 1,2,5,-THIADIAZOLE DERIVATIVES | FMC CORPORATION (US) | 2005-01-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060241097-A1 | Pesticidal substituted 1,2,5-thiadiazole derivatives | DDT, ACHE, O60361 | SIGMAR1 3733/4885CHRM1 345/4885ALDH1A1 224/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.