SCHEMBL5932166

SCHEMBL5932166

CCCOCCCOCCCN

nearest known ligand 0.67

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.47
DNM1 Q05193 8/20 0.41
TSHR P16473 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.41
ODC1 P11926 1/20 0.41
EPHX1 P07099 1/20 0.41
HTT P42858 2/20 0.39
THRB P10828 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL238386 0.97
SCHEMBL5933092 0.94 CYP3A4 (0.47) CYP3A4DNM1TSHRMEN1KMT2A
Hydrochloric Acid SCHEMBL3993420 0.94
SCHEMBL408893 0.94 CYP3A4 (0.47) CYP3A4DNM1TSHRMEN1KMT2A
SCHEMBL5933173 0.94 CYP3A4 (0.47) CYP3A4DNM1TSHRMEN1KMT2A
SCHEMBL11285048 0.92 HTT (0.47) CYP3A4DNM1TSHRMEN1KMT2A
SCHEMBL5932250 0.92 DNM1 (0.46) CYP3A4DNM1TSHRMEN1KMT2A
SCHEMBL20372773 0.90 DNM1 (0.50) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL5932502 0.89 TSHR (0.40) CYP3A4DNM1TSHRMEN1KMT2A
SCHEMBL5932795 0.89 TSHR (0.52) CYP3A4DNM1TSHRMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11833208-B2 PLK1 selective degradation inducing compound UPPTHERA, INC. (KR) 2023-12-05 US disclosed
US-20230372498-A1 PLK1 SELECTIVE DEGRADATION INDUCING COMPOUND UPPTHERA (KR) 2023-11-23 US disclosed
US-20060088786-A1 Rewritable optical information recording medium, recording and reproducing methods, as well as recording and reproducing apparatus MITSUI CHEMICALS, INC. (JP) 2006-04-27 US disclosed
EP-1484191-A1 REWRITABLE OPTICAL INFORMATION RECORDING MEDIUM AND RECORDING/REPRODUCING METHOD, RECORDING/REPRODUCING DEVICE Sony Corporation (JP) 2004-12-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230372498-A1 PLK1 SELECTIVE DEGRADATION INDUCING COMPOUND PLK1, BUB1B, BUB1 CYP3A4 3814/4885DNM1 849/4885TSHR 4252/4885
US-20060088786-A1 Rewritable optical information recording medium, recording and reproducing methods, as well as recording and reproducing apparatus ALPG, TRPC6, GNRHR CYP3A4 3876/4885DNM1 2072/4885TSHR 1237/4885
US-11833208-B2 PLK1 selective degradation inducing compound PLK1, BUB1B, BUB1 CYP3A4 3814/4885DNM1 849/4885TSHR 4252/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.