SCHEMBL408893

SCHEMBL408893

CCCOCCOCCOCCCN

nearest known ligand 0.67

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.47
DNM1 Q05193 7/20 0.41
TSHR P16473 3/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
ALDH1A1 P00352 1/20 0.41
ODC1 P11926 1/20 0.41
EPHX1 P07099 1/20 0.41
THRB P10828 1/20 0.41
HTT P42858 1/20 0.41
MAPT P10636 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5933173 1.00 CYP3A4 (0.47) CYP3A4DNM1TSHRMEN1KMT2A
SCHEMBL238386 0.97
SCHEMBL5932166 0.94 CYP3A4 (0.47) CYP3A4DNM1TSHRMEN1KMT2A
Hydrochloric Acid SCHEMBL3993420 0.94
SCHEMBL5933092 0.94 CYP3A4 (0.47) CYP3A4DNM1TSHRMEN1KMT2A
SCHEMBL11715376 0.93 CYP3A4 (0.42) CYP3A4DNM1TSHRMEN1KMT2A
SCHEMBL11285048 0.92 HTT (0.47) CYP3A4DNM1TSHRMEN1KMT2A
SCHEMBL5933618 0.92 DNM1 (0.46) CYP3A4DNM1TSHRMEN1KMT2A
SCHEMBL16158120 0.90 DNM1 (0.50) DNM1TSHRMEN1KMT2AALDH1A1
SCHEMBL14231347 0.90 DNM1 (0.50) DNM1TSHRMEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3634474-B1 TARGETING MODULES FOR UNIVERSAL CHIMERIC ANTIGEN RECEPTOR EXPRESSING IMMUNE CELLS AND USE IN THE TREATMENT OF CANCER INFECTIONS AND AUTOIMMUNE DISORDERS AVENCELL EUROPE GMBH (DE) 2026-05-06 EP disclosed
US-12173063-B2 Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer, infections and autoimmune disorders AVENCELL EUROPE GMBH (DE) 2024-12-24 US disclosed
US-20240067952-A1 REPROGRAMMING UROKINASE INTO AN ANTIBODY-RECRUITING ANTICANCER AGENT UNIV YALE (US) 2024-02-29 US disclosed
US-20230381113-A1 POLYMERS AND NANOPARTICLE FORMULATIONS FOR SYSTEMIC NUCLEIC ACID DELIVERY THE JOHNS HOPKINS UNIVERSTY 2023-11-30 US disclosed
US-20230295105-A1 PIPERIDINEDIONE DERIVATIVES INNOCURE THERAPEUTICS, INC. (KR) 2023-09-21 US disclosed
US-20230272066-A1 TARGETING MODULES FOR UNIVERSAL CHIMERIC ANTIGEN RECEPTOR EXPRESSING IMMUNE CELLS AND USE IN THE TREATMENT OF CANCER, INFECTIONS AND AUTOIMMUNE DISORDERS AVENCELL THERAPEUTICS, INC. 2023-08-31 US disclosed
US-20230250053-A1 PROCESS FOR SYNTHESIZING TARGETING MOLECULES BRISTOL-MYERS SQUIBB COMPANY 2023-08-10 US disclosed
US-11633460-B2 Injectable solution at pH 7 comprising at least one basal insulin wherein the pI is comprised from 5.8 to 8.5 and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals ADOCIA (FR) 2023-04-25 US disclosed
US-11560426-B2 Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer infections and autoimmune disorders AVENCELL EUROPE GMBH (DE) 2023-01-24 US disclosed
EP-4116298-A1 PIPERIDINEDIONE DERIVATIVE Innocure Therapeutics, Inc. (KR) 2023-01-11 EP disclosed
US-8076288-B2 Hybrid polypeptides having glucose lowering activity AMYLIN PHARMACEUTICALS, INC. (US) 2011-12-13 US disclosed
US-20110262366-A1 COMPOUNDS FOR TARGETING ENDOTHELIAL CELLS, COMPOSITIONS CONTAINING THE SAME AND METHODS FOR THEIR USE BRACCO INTERNATIONAL B.V. (NL) 2011-10-27 US disclosed
CN-1961000-B Hybrid polypeptides with selectable properties AMYLIN PHARMACEUTICALS INC 2011-05-04 CN disclosed
US-7884183-B2 also targeting tumor cells that express vascular endothelial growth factor neuropilin-1 receptor; radiotherapy; radiopharmaceuticals; treating angiogenesis BRACCO SUISSE SA (CH) 2011-02-08 US disclosed
US-20100311903-A1 Photonic Shell-Core Cross Linked and Functionalized Nanostructures for Biological Applications MALLINCKRODT LLC 2010-12-09 US disclosed
US-7820621-B2 Compounds for targeting endothelial cells, compositions containing the same and methods for their use BRACCO INTERNATIONAL B.V. (NL) 2010-10-26 US disclosed
CN-101432025-A Peptide-peptidase inhibitor conjugates and methods of using same AMYLIN PHARMACEUTICALS INC (US) 2009-05-13 CN disclosed
CN-1961000-A Hybrid polypeptides with selectable properties AMYLIN PHARMACEUTICALS INC (US) 2007-05-09 CN disclosed
US-20060293232-A1 Hybrid polypeptides with selectable properties AMYLIN PHARMACEUTICALS, INC. (US) 2006-12-28 US disclosed
WO-2006095234-A2 INTEGRIN TARGETED SYNTHETIC LIGANDS FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS BRACCO IMAGING S.P.A. (IT) 2006-09-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230272066-A1 TARGETING MODULES FOR UNIVERSAL CHIMERIC ANTIGEN RECEPTOR EXPRESSING IMMUNE CELLS AND USE IN THE TREATMENT OF CANCER, INFECTIONS AND AUTOIMMUNE DISORDERS CD74, HAVCR2, CD4 CYP3A4 4847/4885DNM1 3788/4885TSHR 746/4885
US-11633460-B2 Injectable solution at pH 7 comprising at least one basal insulin wherein the pI is comprised from 5.8 to 8.5 and a co-polyamino acid bearing carboxylate charges and hydrophobic radicals IAPP, HBB, IGF1R CYP3A4 4034/4885DNM1 866/4885TSHR 1343/4885
US-20060293232-A1 Hybrid polypeptides with selectable properties IAPP, IGFBP1, PGF CYP3A4 4838/4885DNM1 239/4885TSHR 808/4885
US-20230381113-A1 POLYMERS AND NANOPARTICLE FORMULATIONS FOR SYSTEMIC NUCLEIC ACID DELIVERY SARNP, EEA1, PHAX CYP3A4 4581/4885DNM1 1042/4885TSHR 3202/4885
US-20230295105-A1 PIPERIDINEDIONE DERIVATIVES CRBN, CUL1, PSMB10 CYP3A4 4750/4885DNM1 2444/4885TSHR 3860/4885
US-11560426-B2 Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer infections and autoimmune disorders CD74, HAVCR2, CD4 CYP3A4 4862/4885DNM1 3649/4885TSHR 748/4885
US-20240067952-A1 REPROGRAMMING UROKINASE INTO AN ANTIBODY-RECRUITING ANTICANCER AGENT PLAUR, CD47, CD14 CYP3A4 4736/4885DNM1 2864/4885TSHR 1054/4885
US-12173063-B2 Targeting modules for universal chimeric antigen receptor expressing immune cells and use in the treatment of cancer, infections and autoimmune disorders CD74, HAVCR2, CD4 CYP3A4 4847/4885DNM1 3788/4885TSHR 746/4885
US-20110262366-A1 COMPOUNDS FOR TARGETING ENDOTHELIAL CELLS, COMPOSITIONS CONTAINING THE SAME AND METHODS FOR THEIR USE VCAM1, FLT1, EDNRA CYP3A4 4836/4885DNM1 640/4885TSHR 1504/4885
US-20230250053-A1 PROCESS FOR SYNTHESIZING TARGETING MOLECULES RARG, RARA, RARB CYP3A4 4109/4885DNM1 1743/4885TSHR 1440/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.