Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 3/20 | 0.58 |
| ▸ | CA2 | P00918 | 3/20 | 0.58 |
| ▸ | CA1 | P00915 | 2/20 | 0.58 |
| ▸ | IL1RN | P18510 | 1/20 | 0.56 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA9 | Q16790 | 3/20 | 0.47 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CTSD | P07339 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL874722 | 0.79 | KEAP1 (0.58) | KEAP1CA2CA1IL1RNERAP1 | |
| SCHEMBL59151 | 0.78 | KEAP1 (0.64) | KEAP1CA2CA1IL1RNERAP1 | |
| SCHEMBL6005110 | 0.78 | CA2 (0.64) | KEAP1CA2CA1IL1RNERAP1 | |
| SCHEMBL23141160 | 0.76 | KEAP1 (0.61) | KEAP1CA2CA1IL1RNERAP1 | |
| SCHEMBL31219811 | 0.75 | KEAP1 (0.67) | KEAP1CA2CA1IL1RNERAP1 | |
| SCHEMBL5378696 | 0.74 | CA2 (0.58) | KEAP1CA2CA1IL1RNERAP1 | |
| Phenylsulfamide SCHEMBL253104 | 0.74 | CA1 (1.00) | KEAP1CA2CA1IL1RNERAP1 | |
| SCHEMBL22250390 | 0.74 | CA2 (0.58) | KEAP1CA2CA1IL1RNERAP1 | |
| SCHEMBL56693 | 0.74 | KEAP1 (1.00) | KEAP1CA2CA1IL1RNERAP1 | |
| SCHEMBL146561 | 0.74 | CA2 (0.58) | KEAP1CA2CA1IL1RNERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 687 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110143939-A1 | QUINOXALIN-2-ONE DERIVATIVES, COMPOSITIONS WHICH PROTECT USEFUL PLANTS AND COMPRISE THESE DERIVATIVES, AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | BAYER CROPSCIENCE AG (DE) | 2011-06-16 | — | — | US | claimed |
| EP-1549648-B1 | BICYCLIC HETEROAROMATIC COMPOUNDS AS KINASE INHIBITORS | UCB PHARMA SA (BE) | 2008-11-12 | — | — | EP | claimed |
| EP-1187816-B1 | 5-CYANO-2-AMINOPYRIMIDINE DERIVATIVES | CELLTECH R&D LTD (GB) | 2006-12-20 | — | — | EP | claimed |
| EP-1084119-B1 | AROMATIC AMINE DERIVATIVES AS PHARMACEUTICAL AGENTS | CELLTECH THERAPEUTICS LTD (GB) | 2004-09-08 | — | — | EP | claimed |
| EP-0989985-B1 | FUSED POLYCYCLIC 2-AMINOPYRIMIDINE DERIVATIVES AS PROTEIN KINASE INHIBITORS | CELLTECH THERAPEUTICS LTD (GB) | 2003-11-05 | — | — | EP | claimed |
| US-6599908-B1 | Potent and selective inhibitors of the protein tyrosine kinases p56lck and p59fyn | CELLTECH R & D LIMITED (GB) | 2003-07-29 | — | — | US | claimed |
| EP-0934304-B1 | 2-PYRIMIDINEAMINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | CELLTECH THERAPEUTICS LTD (GB) | 2003-02-26 | — | — | EP | claimed |
| EP-0766670-B1 | TRI-SUBSTITUTED PHENYL DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH R&D LTD (GB) | 2002-03-27 | — | — | EP | claimed |
| EP-0766673-B1 | SUBSTITUTED OXIME DERIVATIVES USEFUL AS PDE IV INHIBITORS | CELLTECH CHIROSCIENCE LTD (GB) | 2002-01-30 | — | — | EP | claimed |
| US-6057329-A | Fused polycyclic 2-aminopyrimidine derivatives | CELLTECH THERAPEUTICS LIMITED (GB) | 2000-05-02 | — | — | US | claimed |
| US-5753595-A | Herbicidal 3-(substituted benzoxazol-7-yl) and 3-(Substituted benzothiazol-7-yl)-1-substituted-6-trifluoromethyl-2 4-(1h 3h)pyrimidinediones | FMC CORPORATION (US) | 1998-05-19 | — | — | US | claimed |
| CN-117581124-A | Resin film for polarizing plate, method for producing same, polarizing plate, and display device | 柯尼卡美能达株式会社 | 2024-02-20 | — | — | CN | disclosed |
| WO-2023112722-A1 | COMPOUND, POLYMERIZABLE COMPOSITION, OPTICAL ANISOTROPIC MEMBRANE, OPTICAL FILM, POLARIZING PLATE, AND IMAGE DISPLAY APPARATUS | 富士フイルム株式会社 | 2023-06-22 | — | — | WO | disclosed |
| EP-3015514-B1 | AQUEOUS INK COMPOSITION, INKJET RECORDING METHOD, AND COLORED MATERIAL | NIPPON KAYAKU KK (JP) | 2017-02-01 | — | — | EP | disclosed |
| US-20160280999-A1 | POLARIZING FILM, DISPLAY DEVICE AND PRODUCTION PROCESS THEREOF | FUJIFILM CORPORATION (JP) | 2016-09-29 | — | — | US | disclosed |
| EP-0185506-A2 | Light-sensitive silver halide photographic material | KONICA CORPORATION (JP) | 1986-06-25 | — | — | EP | disclosed |
| EP-0182486-A1 | Silver halide color photographic material | KONICA CORPORATION (JP) | 1986-05-28 | — | — | EP | disclosed |
| EP-0178794-A1 | Silver halide color photographic material | KONICA CORPORATION (JP) | 1986-04-23 | — | — | EP | disclosed |
| EP-0178165-A1 | Silver halide color photographic material | KONICA CORPORATION (JP) | 1986-04-16 | — | — | EP | disclosed |
| US-H42-H | Silver halide color photographic material | FUJI PHOTO FILM CO., LTD. (JP) | 1986-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110143939-A1 | QUINOXALIN-2-ONE DERIVATIVES, COMPOSITIONS WHICH PROTECT USEFUL PLANTS AND COMPRISE THESE DERIVATIVES, AND PROCESSES FOR THEIR PREPARATION AND THEIR USE | QSOX1, PRDX2, NQO2 | KEAP1 20/4885CA2 775/4885CA1 1868/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.