Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3173845 | 0.89 | S1PR1 (0.52) | S1PR1S1PR5MAOBRAB9ANPC1 | |
| SCHEMBL4163135 | 0.81 | S1PR1 (0.46) | S1PR1S1PR5MAOBL3MBTL1TDP1 | |
| SCHEMBL6495585 | 0.77 | ALDH1A1 (0.42) | PKML3MBTL1HPGDSMN1; SMN2PDIA6 | |
| SCHEMBL5277439 | 0.77 | CA1 (0.49) | RAB9ANPC1L3MBTL1TDP1FFAR1 | |
| SCHEMBL4167398 | 0.77 | MGLL (0.49) | RAB9ANPC1L3MBTL1TDP1AR | |
| SCHEMBL2076848 | 0.75 | TSHR (0.50) | MAOBRAB9ANPC1MAOAPKM | |
| SCHEMBL214564 | 0.75 | RAB9A (0.46) | MAOBRAB9ANPC1MAOAL3MBTL1 | |
| SCHEMBL5936645 | 0.75 | MEN1 (0.53) | MAOBRAB9ANPC1PKML3MBTL1 | |
| SCHEMBL4173929 | 0.74 | S1PR1 (0.46) | S1PR1S1PR5MAOBL3MBTL1TDP1 | |
| SCHEMBL5936691 | 0.74 | S1PR1 (0.45) | S1PR1MAOBRAB9ANPC1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060035844-A1 | Preventive or remedy for diseases caused by hyperglycemia | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2006-02-16 | — | — | US | disclosed |
| EP-1568380-A1 | PREVENTIVE OR REMEDY FOR DISEASES CAUSED BY HYPERGLYCEMIA | Kissei Pharmaceutical Co., Ltd. (JP) | 2005-08-31 | — | — | EP | disclosed |