SCHEMBL59411

SCHEMBL59411

C=C(C)C(=O)NCNC(=O)C(=C)C

nearest known ligand 0.41

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.41
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 3/20 0.38
MAPK1 P28482 2/20 0.38
TSHR P16473 2/20 0.38
KDM4E B2RXH2 2/20 0.35
THRB P10828 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
HIF1A Q16665 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11866190 0.92 TGFBR1 (0.38) TGFBR1ALDH1A1TDP1MAPK1TSHR
SCHEMBL3279779 0.89
SCHEMBL1071535 0.88 TDP1 (0.42) TGFBR1ALDH1A1TDP1MAPK1TSHR
SCHEMBL11337975 0.86 TGFBR1 (0.34) TGFBR1ALDH1A1TDP1MAPK1TSHR
SCHEMBL316585 0.84 THRB (0.57) TGFBR1ALDH1A1TDP1TSHRTHRB
SCHEMBL14761394 0.84 ALDH1A1 (0.67) TGFBR1ALDH1A1TDP1MAPK1TSHR
SCHEMBL13113008 0.84 TGFBR1 (0.37) TGFBR1ALDH1A1KDM4E
SCHEMBL13101251 0.84 TGFBR1 (0.37) TGFBR1ALDH1A1KDM4E
SCHEMBL3286234 0.83 TGFBR1 (0.35) TGFBR1ALDH1A1TDP1KDM4ETHRB
SCHEMBL316224 0.82 TGFBR1 (0.41) TGFBR1ALDH1A1TDP1MAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 9864 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6352782-B1 None US claimed
US-12570784-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-03-10 US claimed
US-20260042269-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
US-20260003210-A1 DIFFRACTIVE CONTACT LENSES ALCON INC (CH) 2026-01-01 US claimed
US-20250387989-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2025-12-25 US claimed
EP-4657145-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
EP-4657144-A2 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES Alcon Inc. (CH) 2025-12-03 EP claimed
US-20250298042-A1 ENGINEERED PARTICLES AS RED BLOOD CELL MIMICS AND COMPOSITIONS CONTAINING SAME FOR HEMATOLOGY SLINGSHOT BIOSCIENCES, INC. (US) 2025-09-25 US claimed
US-4107135-A DAPPLED E. I. DU PONT DE NEMOURS AND COMPANY (US) 1978-08-15 US claimed
US-4107384-A Method for producing porous fibers MITSUBISHI RAYON CO., LTD. (JP) 1978-08-15 US claimed
US-4101269-A Dyed polymers and copolymers having a cyanovinyl-azo dye incorporated in the structure thereof PRODUITS CHIMIQUES UGINE KUHLMANN (FR) 1978-07-18 US claimed
US-4064287-A Process for treating selected areas of a surface with solder DYNACHEM CORPORATION (US) 1977-12-20 US claimed
US-4059552-A THICKENER THE DOW CHEMICAL COMPANY (US) 1977-11-22 US claimed
US-4031037-A Three-dimensional polymeric gel materials containing phosphoric acid residues capable of dissociation and a method for their preparation KALAL JAROSLAV 1977-06-21 US claimed
US-4025348-A DI-UNSATURATED COMPOUND, POLYMER WITH TETRAHYDROFURFURYL OR N-ALKOXYMETHYLCARBAMOYL GROUPS, DIEPOXIDE, SENSITIZER, CURING AGENT HITACHI CHEMICAL COMPANY, LTD. (JA) 1977-05-24 US claimed
US-4012362-A COMPLEXING AGENTS, POLYMERS OF ACRYLIC AMIDES OR ESTERS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-15 US claimed
US-4003877-A Photopolymerizable screen printing inks for permanent coatings prepared from aryloxyalkyl compositions DYNACHEM CORPORATION (US) 1977-01-18 US claimed
US-3931355-A SILYL ETHER OF A TETRAARYL 1,2 GLYCOL CATALYST BAYER AKTIENGESELLSCHAFT (DT) 1976-01-06 US claimed