Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PADI1 | Q9ULC6 | 5/20 | 0.42 |
| ▸ | PADI4 | Q9UM07 | 5/20 | 0.42 |
| ▸ | PADI2 | Q9Y2J8 | 4/20 | 0.42 |
| ▸ | PDE4A | P27815 | 3/20 | 0.42 |
| ▸ | PADI3 | Q9ULW8 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.42 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.38 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9662910 | 1.00 | PADI1 (0.42) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL7381619 | 0.86 | KISS1R (0.47) | GRIA1KISS1R | |
| SCHEMBL7156268 | 0.84 | CA1 (0.40) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL11328555 | 0.83 | PADI1 (0.42) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL7888149 | 0.82 | NOS1 (0.40) | ALDH1A1HTT | |
| SCHEMBL1765973 | 0.82 | PADI1 (0.43) | PADI1PADI4PADI2PDE4APADI3 | |
| Hydrochloric Acid SCHEMBL7876078 | 0.81 | NOS1 (0.39) | ALDH1A1HTT | |
| SCHEMBL10654174 | 0.81 | PADI1 (0.46) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL28323687 | 0.81 | C3AR1 (0.44) | PADI1PADI4PADI2PDE4APADI3 | |
| SCHEMBL10946109 | 0.81 | PADI1 (0.60) | PADI1PADI4PADI2PDE4APADI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015077771-A1 | ORDERED MACROPOROUS HYDROGELS FOR BIORESPONSIVE PROCESSES | CARNEGIE MELLON UNIVERSITY (US) | 2015-05-28 | — | — | WO | disclosed |
| US-8343351-B2 | Membrane for removing proteases from liquids | SARTORIUS AG (DE) | 2013-01-01 | — | — | US | disclosed |
| US-8343350-B2 | Membrane, device and method for removing proteases from liquids | SARTORIUS AG (DE) | 2013-01-01 | — | — | US | disclosed |
| US-20060216807-A1 | Membrane for removing proteases from liquids | SARTORIUS AG | 2006-09-28 | — | — | US | disclosed |
| US-20050245431-A1 | Membrane, device and method for removing proteases from liquids | SARTORIUS AG | 2005-11-03 | — | — | US | disclosed |
| US-5073487-A | Rapid assay for functional human α1 -proteinase inhibitor | ATHENS RESEARCH AND TECHNOLOGY, INC. (US) | 1991-12-17 | — | — | US | disclosed |
| EP-0455733-A1 | RAPID ASSAY FOR FUNCTIONAL HUMAN ALPHA 1?-PROTEINASE INHIBITOR | ATHENS RESEARCH AND TECHNOLOGY, INC. (US) | 1991-11-13 | — | — | EP | disclosed |
| WO-1990008837-A1 | RAPID ASSAY FOR FUNCTIONAL HUMAN ALPHA1-PROTEINASE INHIBITOR | ATHENS RESEARCH AND TECHNOLOGY, INC. (US) | 1990-08-09 | — | — | WO | disclosed |