Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.40 |
| ▸ | NOS2 | P35228 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.35 |
| ▸ | NPY4R | P50391 | 7/20 | 0.35 |
| ▸ | NPY1R | P25929 | 5/20 | 0.35 |
| ▸ | NPY2R | P49146 | 4/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7876078 | 0.99 | NOS1 (0.39) | NOS1NOS3NOS2ANPEPRNPEP | |
| SCHEMBL30553031 | 0.83 | MAPT (0.38) | NPY4RNPY1RALDH1A1 | |
| SCHEMBL9662910 | 0.82 | PADI1 (0.42) | ALDH1A1HTT | |
| SCHEMBL5943119 | 0.82 | PADI1 (0.42) | ALDH1A1HTT | |
| SCHEMBL9391207 | 0.81 | DPP7 (0.43) | NOS1NOS3NOS2 | |
| SCHEMBL7445644 | 0.80 | NPY4R (0.35) | ANPEPRNPEPDNPEPNPY4RNPY1R | |
| SCHEMBL27342871 | 0.78 | CYP1A2 (0.40) | ANPEPALDH1A1 | |
| SCHEMBL7717724 | 0.78 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL22346178 | 0.78 | ALDH1A1 (0.44) | ALDH1A1 | |
| SCHEMBL7166055 | 0.78 | ANPEP (0.36) | NOS1NOS3NOS2ANPEPRNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802986-B1 | METHODS OF DETERMINING ENDOGENOUS THROMBIN POTENTIAL (ETP) AND THROMBIN SUBSTRATES FOR USE IN SAID METHODS | HEMKER HENDRIK COENRAAD (NL) | 2001-09-19 | — | — | EP | disclosed |
| US-6207399-B1 | USING A DIPEPTIDE THROMBIN SUBSTRATE OR SALT THAT IS SOLUBLE IN THE SAMPLE CONSISTING OF HEPARIN AND OTHER ANTICOAGULANTS, TO DETERMINE THE ENDOGENOUS THROMBIN POTENTIAL | Hemker, Hendrik Coenraad (NL) | 2001-03-27 | — | — | US | disclosed |
| EP-0802986-A1 | METHODS OF DETERMINING ENDOGENOUS THROMBIN POTENTIAL (ETP) AND THROMBIN SUBSTRATES FOR USE IN SAID METHODS | Hemker, Hendrik Coenraad (NL) | 1997-10-29 | — | — | EP | disclosed |
| WO-1996021740-A1 | METHODS OF DETERMINING ENDOGENOUS THROMBIN POTENTIAL (ETP) AND THROMBIN SUBSTRATES FOR USE IN SAID METHODS | HEMKER HENDRIK COENRAAD (NL) | 1996-07-18 | — | — | WO | disclosed |