Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5944978 | 0.82 | ALDH1A1 (0.51) | KDM4EALDH1A1LMNAMAPK1HPGD | |
| SCHEMBL5944805 | 0.80 | KDM4E (0.52) | KDM4EALDH1A1LMNAMAPK1HPGD | |
| SCHEMBL5944788 | 0.78 | MAPK1 (0.44) | KDM4EALDH1A1LMNAMAPK1HPGD | |
| SCHEMBL5944591 | 0.77 | POLB (0.42) | KDM4EALDH1A1LMNAMAPK1HPGD | |
| SCHEMBL5944684 | 0.77 | POLB (0.42) | KDM4EALDH1A1LMNAMAPK1HPGD | |
| SCHEMBL31144992 | 0.72 | KCNH3 (0.50) | KDM4EALDH1A1LMNAMAPK1HPGD | |
| SCHEMBL5944990 | 0.71 | MAPK1 (0.43) | KDM4EALDH1A1LMNAMAPK1HPGD | |
| SCHEMBL5944627 | 0.71 | ADRA2A (0.38) | MAPT | |
| SCHEMBL456092 | 0.71 | GAA (0.58) | KDM4EALDH1A1LMNAMAPK1HPGD | |
| SCHEMBL5945061 | 0.70 | MAPK1 (0.42) | KDM4EALDH1A1LMNAMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060156481-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | claimed |
| US-20060156481-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | THE PROCTER & GAMBLE COMPANY (US) | 2006-07-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060156481-A1 | Keratin dyeing compounds, keratin dyeing compositions containing them, and use thereof | KRT18, KRTCAP2, NOX5 | KDM4E 1023/4885ALDH1A1 850/4885LMNA 479/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.