Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | BDKRB1 | P46663 | 8/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951113 | 1.00 | HTR1A (0.49) | HTR1ADRD2KCNH2HTR2ABDKRB1 | |
| SCHEMBL3535129 | 0.86 | HTR1A (0.47) | HTR1ADRD2KCNH2HTR2ABDKRB1 | |
| SCHEMBL3535131 | 0.86 | HTR1A (0.47) | HTR1ADRD2KCNH2HTR2ABDKRB1 | |
| SCHEMBL3534842 | 0.80 | BDKRB1 (0.44) | HTR1ADRD2KCNH2HTR2ABDKRB1 | |
| SCHEMBL3534846 | 0.80 | BDKRB1 (0.44) | HTR1ADRD2KCNH2HTR2ABDKRB1 | |
| SCHEMBL22868047 | 0.78 | LMNA (0.53) | BDKRB1HTTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL29741228 | 0.78 | KMT2A (0.50) | BDKRB1HTTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5951102 | 0.75 | BDKRB1 (0.42) | BDKRB1HTTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL5951106 | 0.75 | BDKRB1 (0.42) | BDKRB1HTTTAS1R3TAS1R1TAS1R2 | |
| SCHEMBL15006999 | 0.75 | HTT (0.63) | HTTTAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060111347-A1 | Substituted sulfones and methods of use | AMGEN INC. (US) | 2006-05-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060111347-A1 | Substituted sulfones and methods of use | SULT2A1, STS, SULT1A1 | HTR1A 2883/4885DRD2 4207/4885KCNH2 2255/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.