Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 9/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 5/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1593230 | 0.83 | — | — | |
| SCHEMBL8585311 | 0.73 | ALDH1A1 (0.32) | TDP1CYP3A4ALDH1A1TP53 | |
| SCHEMBL904638 | 0.71 | ACHE (0.53) | ACHETDP1ALDH1A1TSHR | |
| SCHEMBL320609 | 0.71 | MEN1 (1.00) | MEN1MAPTKMT2AACHETDP1 | |
| SCHEMBL27981 | 0.71 | — | — | |
| SCHEMBL11412373 | 0.69 | TDP1 (0.43) | MEN1MAPTKMT2AACHETDP1 | |
| SCHEMBL2392186 | 0.69 | LMNA (0.50) | MEN1KMT2ACYP3A4ALDH1A1TP53 | |
| SCHEMBL979413 | 0.69 | ACHE (0.45) | ACHEAPPLOXL2TAAR1 | |
| SCHEMBL5952745 | 0.69 | CYP2A6 (0.50) | TDP1ALDH1A1MAPK1ALOX15TSHR | |
| SCHEMBL5951790 | 0.69 | CYP3A4 (0.50) | MEN1MAPTKMT2AACHECYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038070-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2006-05-02 | — | — | US | disclosed |
| US-6963017-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2005-11-08 | — | — | US | disclosed |
| EP-0968158-B1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | EP | disclosed |
| US-20050033076-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2005-02-10 | — | — | US | disclosed |
| US-20030009046-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2003-01-09 | — | — | US | disclosed |
| US-4977288-A | M-aminophenyltrialkylstannane | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1990-12-11 | — | — | US | disclosed |
| WO-1989007097-A1 | RADIOHALOGENATED BIOTIN AND INTERMEDIATES THEREFOR | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 1989-08-10 | — | — | WO | disclosed |
| EP-0001717-B1 | INSECTICIDAL COMPOSITIONS CONTAINING TETRAORGANOTIN COMPOUNDS AND METHOD FOR USING SAME | M & T CHEMICALS, INC. (US) | 1981-11-04 | — | — | EP | disclosed |
| US-4212885-A | Insecticidal compositions containing certain tetraorganotin compounds and method for using same | M&T CHEMICALS INC. (US) | 1980-07-15 | — | — | US | disclosed |
| EP-0001717-A2 | Insecticidal compositions containing tetraorganotin compounds and method for using same | M & T CHEMICALS, INC. (US) | 1979-05-02 | — | — | EP | disclosed |
| US-4138483-A | Insecticidal compositions containing certain tetraorganotin compounds and method for using same | M&T CHEMICALS INC. (US) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050033076-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP2J2, IDH3A | MEN1 718/4885MAPT 3693/4885KMT2A 3372/4885 |
| US-20030009046-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP1B1, CYP1A1 | MEN1 614/4885MAPT 3748/4885KMT2A 3578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.