Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP11 | Q9NR21 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.39 |
| ▸ | HTR7 | P34969 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.38 |
| ▸ | IL1RN | P18510 | 1/20 | 0.38 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.38 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | CDC25A | P30304 | 1/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5951742 | 0.80 | HTR7 (0.43) | HTR1AHTR7ACHEBRD4SLC6A3 | |
| SCHEMBL2486074 | 0.79 | PIM1 (0.41) | PARP10PARP11ACHEBRD4 | |
| SCHEMBL5952742 | 0.79 | ACHE (0.40) | HTR1AHTR7ACHEBRD4CREBBP | |
| SCHEMBL5951268 | 0.79 | ACHE (0.41) | ACHE | |
| SCHEMBL5952596 | 0.78 | HTR1A (0.46) | HTR1AHTR7ACHEANPEPIL1RN | |
| SCHEMBL3066323 | 0.78 | ACHE (0.64) | PARP10PARP11HTR1AHTR7ACHE | |
| SCHEMBL5951436 | 0.78 | GABRG2 (0.43) | HTR7BRD4 | |
| SCHEMBL5952174 | 0.77 | METAP1 (0.39) | PARP10PARP11HTR1AHTR7ACHE | |
| SCHEMBL5952058 | 0.75 | ACHE (0.60) | PARP10PARP11HTR1AHTR7ACHE | |
| SCHEMBL5951603 | 0.75 | METAP1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038070-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2006-05-02 | — | — | US | disclosed |
| US-6963017-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2005-11-08 | — | — | US | disclosed |
| EP-0968158-B1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | EP | disclosed |
| US-6891005-B2 | Bridged metal complexes for gas phase polymerizations | BP CHEMICALS LIMITED (GB) | 2005-05-10 | — | — | US | disclosed |
| US-20050033076-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2005-02-10 | — | — | US | disclosed |
| US-20030199650-A1 | Bridged metal complexes for gas phase polymerizations | BP CHEMICALS LIMITED | 2003-10-23 | — | — | US | disclosed |
| EP-1119575-B1 | BRIDGED METAL COMPLEXES | DOW CHEMICAL CO (US) | 2003-09-03 | — | — | EP | disclosed |
| US-20030009046-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2003-01-09 | — | — | US | disclosed |
| EP-1141034-B1 | BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS | BP CHEM INT LTD (GB) | 2002-10-30 | — | — | EP | disclosed |
| US-6376406-B1 | COORDINATION POLYMERIZATION CATALYSTS FOR ALPHA-OLEFINS | THE DOW CHEMICAL COMPANY | 2002-04-23 | — | — | US | disclosed |
| EP-0834519-B1 | CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN | JAPAN POLYOLEFINS CO LTD (JP) | 2002-03-06 | — | — | EP | disclosed |
| EP-1141034-A2 | BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS | BP Chemicals Limited (GB) | 2001-10-10 | — | — | EP | disclosed |
| US-6284905-B1 | GROUP 4 TRANSITION METAL COMPLEX CONTAINING A BORON OR ALUMINUM BRIDGING GROUP CONTAINING A NITROGEN CONTAINING ELECTRON DONATING GROUP, ESPECIALLY AN AMIDO GROUP; OLEFIN SOLUTION OR SLURRY POLYMERIZATION CATALYSTS | THE DOW CHEMICAL COMPANY | 2001-09-04 | — | — | US | disclosed |
| EP-1119575-A1 | BRIDGED METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2001-08-01 | — | — | EP | disclosed |
| US-6121182-A | A METALLOCENE CATALYST FOR POLYMERIZATION OF ISOTACTIC POLYOLEFINS WITH HIGH RIGIDITY AND HIGH MELTING POINT, USEFUL AS INDUSTRIAL MATERIAL FOR AUTOMOBILES | JAPAN POLYOLAFINS CO., LTD. (JP) | 2000-09-19 | — | — | US | disclosed |
| WO-2000020462-A2 | BRIDGED METAL COMPLEXES FOR GAS PHASE POLYMERIZATIONS | BP CHEMICALS LIMITED (GB) | 2000-04-13 | — | — | WO | disclosed |
| WO-2000020426-A1 | BRIDGED METAL COMPLEXES | THE DOW CHEMICAL COMPANY (US) | 2000-04-13 | — | — | WO | disclosed |
| EP-0834519-A1 | CATALYST FOR POLYOLEFIN PRODUCTION AND PROCESS FOR PRODUCING POLYOLEFIN | Japan Polyolefins Co., Ltd. (JP) | 1998-04-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050033076-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP2J2, IDH3A | PARP10 2016/4885PARP11 2757/4885HTR1A 2570/4885 |
| US-20030009046-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP1B1, CYP1A1 | PARP10 2151/4885PARP11 2439/4885HTR1A 2132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.