Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3469282 | 0.76 | LMNA (0.55) | ALDH1A1TSHRMEN1LMNATHRB | |
| Ethane SCHEMBL29266735 | 0.73 | ALDH1A1 (0.57) | ALDH1A1TSHRHDAC8MEN1LMNA | |
| SCHEMBL29405187 | 0.73 | ALDH1A1 (0.63) | ALDH1A1TSHRHDAC8MEN1LMNA | |
| SCHEMBL7638 | 0.73 | ALDH1A1 (0.63) | ALDH1A1TSHRHDAC8MEN1LMNA | |
| SCHEMBL473080 | 0.73 | ALDH1A1 (0.63) | ALDH1A1TSHRHDAC8MEN1LMNA | |
| SCHEMBL8678832 | 0.73 | TSHR (0.35) | TSHRLMNA | |
| SCHEMBL7684858 | 0.71 | ALDH1A1 (0.40) | ALDH1A1TSHR | |
| Propene SCHEMBL7948571 | 0.71 | ALDH1A1 (0.55) | ALDH1A1TSHRHDAC8MEN1LMNA | |
| Methyl Alcohol SCHEMBL28639807 | 0.71 | ALDH1A1 (0.55) | ALDH1A1TSHRHDAC8MEN1LMNA | |
| SCHEMBL6400185 | 0.70 | ALDH1A1 (0.35) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7038070-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2006-05-02 | — | — | US | disclosed |
| US-6963017-B2 | Preparation of preparing substituted indanones | BASELL POLYOLEFINE GMBH (DE) | 2005-11-08 | — | — | US | disclosed |
| EP-0968158-B1 | METHOD OF PREPARING SUBSTITUTED INDANONES, THE SUBSTITUTED INDANONES AND METALLOCENES PREPARED THEREFROM | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | EP | disclosed |
| US-20050033076-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2005-02-10 | — | — | US | disclosed |
| US-20030009046-A1 | Preparation of preparing substituted indanones | EQUISTAR CHEMICALS, LP | 2003-01-09 | — | — | US | disclosed |
| EP-1066329-A1 | POLYMERIC SUPPORTED CATALYSTS FOR OLEFIN POLYMERIZATION | EXXON CHEMICAL PATENTS INC. (US) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999050311-A1 | POLYMERIC SUPPORTED CATALYSTS FOR OLEFIN POLYMERIZATION | EXXON CHEMICAL PATENTS INC. (US) | 1999-10-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050033076-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP2J2, IDH3A | ALDH1A1 317/4885TSHR 4624/4885HDAC8 3820/4885 |
| US-20030009046-A1 | Preparation of preparing substituted indanones | CYP1A2, CYP1B1, CYP1A1 | ALDH1A1 198/4885TSHR 4667/4885HDAC8 3917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.