SCHEMBL7684858

SCHEMBL7684858

C=CC[Sn](CC=C)(CC=C)c1ccccc1C=C

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.40
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6400185 0.73 ALDH1A1 (0.35) ALDH1A1
SCHEMBL5898869 0.72 ADRB2 (0.41) ALDH1A1
SCHEMBL5952555 0.71 ALDH1A1 (0.44) ALDH1A1TSHR
SCHEMBL4619452 0.69 ALDH1A1 (0.36) ALDH1A1TSHR
SCHEMBL473080 0.68 ALDH1A1 (0.63) ALDH1A1TSHR
SCHEMBL29405187 0.68 ALDH1A1 (0.63) ALDH1A1TSHR
SCHEMBL7638 0.68 ALDH1A1 (0.63) ALDH1A1TSHR
SCHEMBL1176773 0.66 ALDH1A1 (0.60) ALDH1A1TSHR
SCHEMBL8719955 0.66 ALDH1A1 (0.60) ALDH1A1TSHR
SCHEMBL22496001 0.66 ALDH1A1 (0.60) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6426313-B2 CROSSLINKED POLYMERIC BEADS AS CATALYST SUPPORT EXXON MOBIL CHEMICAL PATENTS INC. 2002-07-30 US disclosed
US-20020010079-A1 POLYMERIC SUPPORTED CATALYSTS FOR OLEFIN POLYMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. 2002-01-24 US disclosed
EP-1066329-A1 POLYMERIC SUPPORTED CATALYSTS FOR OLEFIN POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 2001-01-10 EP disclosed
WO-1999050311-A1 POLYMERIC SUPPORTED CATALYSTS FOR OLEFIN POLYMERIZATION EXXON CHEMICAL PATENTS INC. (US) 1999-10-07 WO disclosed