Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6288871 | 0.82 | TDP1 (0.41) | ALDH1A1IAPP | |
| Hexane SCHEMBL10533800 | 0.76 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL1453183 | 0.73 | TSHR (0.36) | ALDH1A1 | |
| SCHEMBL7684858 | 0.73 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL1453289 | 0.73 | HTR1B (0.40) | ALDH1A1 | |
| SCHEMBL3360048 | 0.72 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL3227093 | 0.72 | CYP1A2 (0.44) | ALDH1A1 | |
| SCHEMBL11202895 | 0.72 | TSHR (0.39) | ALDH1A1 | |
| SCHEMBL31558464 | 0.72 | SMN1; SMN2 (0.36) | ALDH1A1 | |
| SCHEMBL3848205 | 0.72 | RECQL (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6974865-B2 | C3′ -methylene hydrogen phosphonate oligomers and related compounds | ISIS PHARMACEUTICALS, INC. (US) | 2005-12-13 | — | — | US | disclosed |
| US-20030139586-A1 | C3' -methylene hydrogen phosphonate oligomers and related compounds | COOK PHILLIP DAN (US) | 2003-07-24 | — | — | US | disclosed |
| US-6414135-B1 | PHOSPHONYLATION OF ALKYLNUCLEOSIDE WITH BIS(TRIMETHYLSILYL)PHOSPHONITE IN BASE PRESENCE; CONCENTRATION; ADDING METHANOL SOLVENT; NUCLEASE RESISTANCE; HYBRIDIZATION | ISIS PHARMACEUTICALS, INC. | 2002-07-02 | — | — | US | disclosed |
| WO-2001002415-A1 | C3'-METHYLENE HYDROGEN PHOSPHONATE MONOMERS AND RELATED COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2001-01-11 | — | — | WO | disclosed |
| WO-2001002419-A1 | C3'-METHYLENE HYDROGEN PHOSPHONATE OLIGOMERS AND RELATED COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2001-01-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030139586-A1 | C3' -methylene hydrogen phosphonate oligomers and related compounds | NT5C3B, NUDT1, MTAP | ALDH1A1 3289/4885IAPP 1393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.