Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 9/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 7/20 | 0.42 |
| ▸ | AR | P10275 | 3/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 4/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6333440 | 0.84 | ESR2 (0.39) | TP53TDP1ESR1ESR2HSD17B1 | |
| SCHEMBL6334648 | 0.84 | ALOX15 (0.42) | TP53TDP1ESR1ESR2TRPA1 | |
| SCHEMBL6336529 | 0.84 | KDM4E (0.39) | ESR1ESR2HSD17B1HSD17B2CYP3A4 | |
| SCHEMBL6342106 | 0.84 | RARB (0.42) | TP53TDP1ESR1ESR2HSD17B2 | |
| SCHEMBL6333099 | 0.81 | CNR2 (0.43) | TDP1ESR1ESR2HSD17B1HSD17B2 | |
| SCHEMBL18763597 | 0.79 | TDP1 (0.64) | TP53TDP1ESR1ESR2TLR8 | |
| SCHEMBL2954728 | 0.79 | MAOB (0.41) | ESR1ESR2ARCYP3A4 | |
| SCHEMBL20136961 | 0.78 | TP53 (0.61) | TP53TDP1ESR1ESR2TLR8 | |
| SCHEMBL673977 | 0.73 | ESR1 (0.70) | TP53TDP1ESR1ESR2AR | |
| SCHEMBL6701961 | 0.72 | HSD17B1 (0.46) | ESR1ESR2ARTLR8HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426513-A | Polycarbonate resins based on polyphenolic compounds | GENERAL ELECTRIC COMPANY (US) | 1984-01-17 | — | — | US | claimed |
| US-7122613-B1 | Method for the production of polycarbonates | GENERAL ELECTRIC COMPANY (US) | 2006-10-17 | — | — | US | disclosed |
| US-20050228167-A1 | Molecular compounds containing polymers having hydrogen bond sites as the constituent compounds | NIPPON SODA CO., LTD. (JP) | 2005-10-13 | — | — | US | disclosed |
| US-20040152022-A1 | Resist remover composition | DONGJIN SEMICHEM CO., LTD. (KR) | 2004-08-05 | — | — | US | disclosed |
| US-6222004-B1 | MOLDABILITY IN BLOW MOLDING; APPEARANCE AND COLOR TONE | IDEMITSU PETROCHEMICAL CO., LTD (JP) | 2001-04-24 | — | — | US | disclosed |
| US-4426513-A | Polycarbonate resins based on polyphenolic compounds | GENERAL ELECTRIC COMPANY (US) | 1984-01-17 | — | — | US | disclosed |