SCHEMBL5953586

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5953572	0.84	POLB (0.42)	ALDH1A1CYP2A13SMN1; SMN2KDM4EPOLB
	Hydrochloric Acid SCHEMBL9056165	0.83	POLB (0.41)	ALDH1A1CYP2A13SMN1; SMN2KDM4EPOLB
	SCHEMBL5953609	0.80	DRD2 (0.48)	ALDH1A1KDM4EHTTLTA4HCYP1A2
	SCHEMBL5953434	0.79	DRD2 (0.47)	ALDH1A1KDM4EHTTLTA4HCYP1A2
	Hydrochloric Acid SCHEMBL9054931	0.78	DRD2 (0.46)	ALDH1A1SMN1; SMN2KDM4EHTTLTA4H
	SCHEMBL5953708	0.73	ALDH1A1 (0.43)	ALDH1A1KDM4EHTTMEN1CYP1A2
	Hydrochloric Acid SCHEMBL9054765	0.72	ALDH1A1 (0.42)	ALDH1A1KDM4EHTTMEN1KMT2A
	SCHEMBL5953188	0.69	DRD2 (0.46)	ALDH1A1CYP2A13SMN1; SMN2KDM4ETSHR
	SCHEMBL8894368	0.69	DRD2 (0.45)	POLBCYP1A2CYP3A4CYP2D6CYP2C19
	SCHEMBL8892053	0.69	SIGMAR1 (0.50)	POLBDRD2DRD4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.