Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD5 | P21918 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953765 | 0.91 | HTR2A (0.33) | HTR2AHTR2BHTR2CDRD2KDM4E | |
| SCHEMBL5954156 | 0.87 | GABRA1 (0.39) | HTR2AHTR2BHTR2CDRD2LMNA | |
| SCHEMBL5953655 | 0.86 | GABRA1 (0.35) | HTR2AHTR2BDRD2KDM4ELMNA | |
| SCHEMBL5954199 | 0.81 | HTR2A (0.36) | HTR2AHTR2BHTR2CDRD2KDM4E | |
| SCHEMBL5954183 | 0.77 | MEN1 (0.33) | — | |
| SCHEMBL2971532 | 0.75 | TRPA1 (0.38) | GABRA1GABRB2 | |
| SCHEMBL5954155 | 0.75 | ADRA2A (0.33) | ADRA2ACYP2D6ADRA2BADRA1A | |
| SCHEMBL5953694 | 0.74 | MEN1 (0.31) | — | |
| SCHEMBL5953581 | 0.73 | BCHE (0.36) | HTR2AHTR2BHTR2C | |
| SCHEMBL21377188 | 0.72 | DRD2 (0.33) | DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1532230-A2 | METHOD AND COMPOSITION FOR USING STABILIZED BETA-CAROTENE AS CETANE IMPROVER IN HYDROCARBONACEOUS DIESEL FUELS | Oryxe Energy International, Inc. (US) | 2005-05-25 | — | — | EP | claimed |
| WO-2003104360-A2 | METHOD AND COMPOSITION FOR USING STABILIZED BETA-CAROTENE AS CETANE IMPROVER IN HYDROCARBONACEOUS DIESEL FUELS | ORYXE ENERGY INTERNATIONAL, INC. (US) | 2003-12-18 | — | — | WO | claimed |
| US-20060052620-A1 | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2006-03-09 | — | — | US | disclosed |
| CN-1653021-A | Preparation of substituted indenes | BASELL POLYOLEFINE GMBH (DE) | 2005-08-10 | — | — | CN | disclosed |
| EP-1492749-A1 | PREPARATION OF SUBSTITUTED INDENES | Basell Polyolefine GmbH (DE) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084904-A1 | PREPARATION OF SUBSTITUTED INDENES | BASELL POLYOLEFINE GMBH (DE) | 2003-10-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060052620-A1 | Preparation of substituted indenes | INTS9, CYP1A2, INF2 | HTR2A 3428/4885HTR2B 2637/4885HTR2C 3399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.