SCHEMBL5953671

SCHEMBL5953671

Cc1[c]c(C)c(-c2ccc(C(C)(C)C)cc2)c(C)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
KIF11 P52732 4/20 0.37
NPC1 O15118 5/20 0.33
RAB9A P51151 5/20 0.33
ALDH1A1 P00352 4/20 0.33
MITF O75030 1/20 0.33
TP53 P04637 1/20 0.33
KMT2A Q03164 1/20 0.33
LMNA P02545 1/20 0.33
TYR P14679 1/20 0.33
CA12 O43570 1/20 0.32
CA9 Q16790 1/20 0.32
KDM4E B2RXH2 3/20 0.32
POLB P06746 2/20 0.32
HPGD P15428 2/20 0.32
ALOX15 P16050 1/20 0.32
HSD17B10 Q99714 1/20 0.32
APOBEC3G Q9HC16 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
RXRB P28702 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2018625 0.77 MAPT (0.35) NPC1RAB9AALDH1A1KMT2ALMNA
SCHEMBL5953676 0.75 TSHR (0.52) TSHRKIF11NPC1RAB9AALDH1A1
SCHEMBL5134086 0.75 KIF11 (0.48) TSHRKIF11NPC1RAB9AALDH1A1
SCHEMBL2652273 0.72 TSHR (0.43) TSHRKIF11NPC1RAB9AALDH1A1
SCHEMBL1765225 0.72 LMNA (0.52) TSHRKIF11ALDH1A1KMT2ALMNA
SCHEMBL9796315 0.71 TSHR (0.39) TSHRKIF11NPC1RAB9AALDH1A1
SCHEMBL5608923 0.69 TSHR (0.48) TSHRKIF11NPC1RAB9AALDH1A1
SCHEMBL16769413 0.67 NPC1 (0.51) TSHRKIF11NPC1RAB9AALDH1A1
SCHEMBL28902397 0.66 POLB (0.30) POLB
SCHEMBL317298 0.66 RAPGEF4 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7147938-B2 Organic element for electroluminescent devices EASTMAN KODAK COMPANY (US) 2006-12-12 US disclosed
US-20060003183-A1 Light emitting diodes with light emitting layers containing a stilbene derivative and a boron complex having an absorption spectrum that overlaps with the emission spectrum of the stilbene derivative; improved brightness EASTMAN KODAK COMPANY 2006-01-05 US disclosed