SCHEMBL317298

SCHEMBL317298

Cc1[c]c(C)c(-c2c(C)cc(C)cc2C)c(C)c1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
RAPGEF4 Q8WZA2 1/20 0.33
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP9 P14780 1/20 0.30
MMP8 P22894 1/20 0.30
MMP13 P45452 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7010710 0.76 ALDH1A1 (0.36) RAPGEF4
SCHEMBL317299 0.76 RAPGEF4 (0.50) RAPGEF4CA1CA2MMP1MMP2
SCHEMBL19534945 0.73 RAPGEF4 (0.31) RAPGEF4
SCHEMBL6612921 0.73 ALDH1A1 (0.34) CA1CA2
SCHEMBL2018625 0.71 MAPT (0.35)
SCHEMBL11487737 0.70 CYP1A2 (0.41)
SCHEMBL395719 0.69
SCHEMBL10987049 0.68 RAPGEF4 (0.31) RAPGEF4
SCHEMBL27887395 0.67
SCHEMBL29196053 0.67 RAPGEF4 (0.30) RAPGEF4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8138348-B2 Using coordination polymerization catalyst EXXONMOBIL CHEMICAL PATENTS INC. (US) 2012-03-20 US claimed
US-20110288327-A1 PROCESS FOR THE MANUFACTURE OF COMPOUNDS COMPRISING NITRILE FUNCTIONAL GROUPS RHODIA OPERATIONS (FR) 2011-11-24 US claimed
EP-2121183-A1 CHROMIUM COMPLEXES OF PYRIDINE BIS (OXAZOLINE)-LIGANDS FOR ETHYLENE DIMERIZATION ExxonMobil Chemical Patents Inc. (US) 2009-11-25 EP claimed
EP-2114973-A1 METHODS FOR OLIGOMERIZING OLEFINS WITH CHROMIUM PYRIDINE THIOETHER CATALYSTS ExxonMobil Chemical Patents Inc. (US) 2009-11-11 EP claimed
EP-2106402-A1 METHODS FOR OLIGOMERIZING OLEFINS WITH CHROMIUM PYRIDINE PHOSPHINO CATALYSTS ExxonMobil Chemical Patents Inc. (US) 2009-10-07 EP claimed
EP-2104679-A1 METHODS FOR OLIGOMERIZING OLEFINS WITH CHROMIUM PYRIDINE MONO-OXAZOLINE CATALYSTS ExxonMobil Chemical Patents Inc. (US) 2009-09-30 EP claimed
US-20080200743-A1 Methods For Oligomerizing Olefins With Chromium Pyridine Ether Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2008-08-21 US claimed
US-20080200626-A1 Methods For Oligomerizing Olefins With Chromium Pyridine Thioether Catalysts SYMYX TECHNOLOGIES, INC. 2008-08-21 US claimed
US-20080188633-A1 Methods For Oligomerizing Olefins With Chromium Pyridine Phosphino Catalysts SYMYX TECHNOLOGIES, INC. 2008-08-07 US claimed
US-20080182951-A1 Chromium Pyridine Bis(Oxazoline) And Related Catalysts For Ethylene Dimerization EXXONMOBIL CHEMICAL PATENTS INC. 2008-07-31 US claimed
US-20080182989-A1 Methods For Oligomerizing Olefins With Chromium Pyridine Mono-Oxazoline Catalysts EXXONMOBIL CHEMICAL PATENTS INC. 2008-07-31 US claimed
WO-2008085657-A1 CHROMIUM COMPLEXES OF PYRIDINE BIS (OXAZOLINE)- LIGANDS FOR ETHYLENE DIMERI ZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-07-17 WO claimed
WO-2008085658-A1 METHODS FOR OLIGOMERIZING OLEFINS WITH CHROMIUM PYRIDINE THIOETHER CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-07-17 WO claimed
WO-2008085655-A1 METHODS FOR OLIGOMERIZING OLEFINS WITH CHROMIUM PYRIDINE MONO-OXAZOLINE CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-07-17 WO claimed
WO-2008085653-A1 METHODS FOR OLIGOMERIZING OLEFINS WITH CHROMIUM PYRIDINE PHOSPHINO CATALYSTS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2008-07-17 WO claimed
US-11214636-B2 Rigid non-cyclopentadienyl group 4 transition metal and rare earth metal catalysts for olefin polymerization MCMASTER UNIVERSITY (CA) 2022-01-04 US disclosed
US-20200308322-A1 RIGID NON-CYCLOPENTADIENYL GROUP 4 TRANSITION METAL AND RARE EARTH METAL CATALYSTS FOR OLEFIN POLYMERIZATION MCMASTER UNIVERSITY (CA) 2020-10-01 US disclosed
US-6166072-A Amino acid derivatives ALLELIX NEUROSCIENCE, INC. (CA) 2000-12-26 US disclosed
US-5252539-A Benzenesulfonyl carboxamide compounds intermediate compounds and method of preparation thereof and use of said compounds and intermediate compounds as herbicidal agents AMERICAN CYANAMID COMPANY (US) 1993-10-12 US disclosed
US-5120854-A Benzenesulfonyl carboxamide compounds and intermediate compounds AMERICAN CYANAMID COMPANY (US) 1992-06-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110288327-A1 PROCESS FOR THE MANUFACTURE OF COMPOUNDS COMPRISING NITRILE FUNCTIONAL GROUPS NIT2, LPO, CNDP2 RAPGEF4 1191/4885CA1 109/4885CA2 91/4885
US-20080200743-A1 Methods For Oligomerizing Olefins With Chromium Pyridine Ether Catalysts OXER1, NOD1, NOD2 RAPGEF4 2022/4885CA1 943/4885CA2 1601/4885
US-20080182989-A1 Methods For Oligomerizing Olefins With Chromium Pyridine Mono-Oxazoline Catalysts OXER1, OXGR1, OXA1L RAPGEF4 4180/4885CA1 636/4885CA2 1430/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.