Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.47 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.44 |
| ▸ | LAP3 | P28838 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | ADH1B | P00325 | 1/20 | 0.31 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 2/20 | 0.30 |
| ▸ | GABRD | O14764 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5953881 | 1.00 | DPP4 (0.47) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL8677957 | 0.80 | — | — | |
| SCHEMBL8318935 | 0.79 | DPP4 (0.45) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL20458836 | 0.77 | DPP4 (0.44) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL5847294 | 0.74 | — | — | |
| SCHEMBL4603090 | 0.73 | DPP4 (0.48) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL4603093 | 0.73 | DPP4 (0.48) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL23169746 | 0.73 | DPP4 (0.53) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL1034777 | 0.73 | DPP4 (0.53) | DPP4DPP8DPP9DPP7FAP | |
| SCHEMBL12285003 | 0.73 | DPP4 (0.53) | DPP4DPP8DPP9DPP7FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7070963-B2 | Amidase from variovorax | DEGUSSA AG (DE) | 2006-07-04 | — | — | US | disclosed |
| US-20030186423-A1 | Amidase from variovorax | DEGUSSA AG (DE) | 2003-10-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030186423-A1 | Amidase from variovorax | NAAA, VARS1, AMD1 | DPP4 225/4885DPP8 157/4885DPP9 211/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.